Longevity for free? Increased reproduction with limited trade-offs in Drosophila melanogaster selected for increased life span

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  • Janneke Wit, Danmark
  • Pernille Merete Sarup, Danmark
  • Nikolett Lupsa, Sgezed University, Ungarn
  • Hans Malte
  • Jane Frydenberg, Danmark
  • Volker Loeschcke
Selection for increased life span in Drosophila melanogaster has been shown to correlate with decreased early fecundity and increased fecundity later in life. This phenomenon has been ascribed to the existence of trade-offs in which limited resources can be invested in either somatic maintenance or reproduction. In our longevity selection lines, we did not find such a trade-off. Rather, we find that females have similar or higher fecundity throughout life compared to non-selected controls. To determine whether increased longevity affects responses in other traits, we looked at several stress resistance traits (chill coma recovery, heat knockdown, desiccation and starvation), geo- tactic behaviour, egg-to-adult viability, body size, developmental time as well as metabolic rate. Longevity select- ed flies were more starvation resistant. However, in females longevity and fecundity were not negatively correlated with the other traits assayed. Males from longevity selected lines were slower at recovering from a chill induced coma and resting metabolic rate increased with age, but did not correlate with life span.
OriginalsprogEngelsk
TidsskriftExperimental Gerontology
Vol/bind48
Nummer3
Sider (fra-til)349-357
Antal sider9
ISSN0531-5565
DOI
StatusUdgivet - mar. 2013

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