Left Atrial Appendage Occlusion and Post-procedural Antithrombotic Management

Anders Kramer, Giuseppe Patti, Jens Erik Nielsen-Kudsk, Sergio Berti, Kasper Korsholm

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

Abstract

Left atrial appendage occlusion (LAAO) is an established alternative to oral anticoagulation for stroke prevention in atrial fibrillation. Antithrombotic therapy is used in the post-procedural period to prevent device-related thrombosis (DRT). The risk of DRT is considered highest in the first 45-90 days after device implantation, based on animal studies of the device healing process. Clinically applied antithrombotic regimens vary greatly across studies, continents, and centers. This article gives an overview of the evidence behind current antithrombotic regimens, ongoing randomized trials, and future post-procedural management.

OriginalsprogEngelsk
Artikelnummer803
TidsskriftJournal of Clinical Medicine
Vol/bind13
Nummer3
ISSN2077-0383
DOI
StatusUdgivet - jan. 2024

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