Investigation of nanoscale structures by small-angle X-ray scattering in a radiochromic dosimeter

Peter Sandegaard Skyt; Grethe Vestergaard Jensen; Isak Hannes Wahlstedt; Jørgen Breede Baltzer Petersen; Ludvig Paul Muren; Jan Skov Pedersen; Peter Balling

doi:10.1039/c3ra46605a

Investigation of nanoscale structures by small-angle X-ray scattering in a radiochromic dosimeter

Peter Sandegaard Skyt^*, Grethe Vestergaard Jensen, Isak Hannes Wahlstedt, Jørgen Breede Baltzer Petersen, Ludvig Paul Muren, Jan Skov Pedersen, Peter Balling

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

3 Citationer (Scopus)

Abstract

This study examines the nanoscale structures in a radiochromic dosimeter that was based on leuco-malachite-green dye and the surfactant sodium dodecyl sulfate (SDS) suspended in a gelatin matrix. Small-angle X-ray scattering was used to investigate the structures of a range of compositions of the dosimeter. When omitting gelatin, ellipsoidal micelles of SDS were formed with a core radius near 15 Å, an eccentricity of 1.6, and a head-group shell thickness near 7 Å. Gelatin significantly changed the micelles to a cylindrical shape with around three times lower core radius and four times larger shell thickness, which shows that the gelatin is present in the shell and the outer part of the core. Insight into the detailed structure might help to improve the dosimeter performance and increase the dose response to clinically relevant dose levels.

Originalsprog	Engelsk
Tidsskrift	R S C Advances
Vol/bind	4
Nummer	18
Sider (fra-til)	9152-9159
Antal sider	8
ISSN	2046-2069
DOI	https://doi.org/10.1039/c3ra46605a
Status	Udgivet - 20 feb. 2014

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10.1039/c3ra46605a

http://www.scopus.com/inward/record.url?scp=84893937696&partnerID=8YFLogxK

Citationsformater

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title = "Investigation of nanoscale structures by small-angle X-ray scattering in a radiochromic dosimeter",

abstract = "This study examines the nanoscale structures in a radiochromic dosimeter that was based on leuco-malachite-green dye and the surfactant sodium dodecyl sulfate (SDS) suspended in a gelatin matrix. Small-angle X-ray scattering was used to investigate the structures of a range of compositions of the dosimeter. When omitting gelatin, ellipsoidal micelles of SDS were formed with a core radius near 15 {\AA}, an eccentricity of 1.6, and a head-group shell thickness near 7 {\AA}. Gelatin significantly changed the micelles to a cylindrical shape with around three times lower core radius and four times larger shell thickness, which shows that the gelatin is present in the shell and the outer part of the core. Insight into the detailed structure might help to improve the dosimeter performance and increase the dose response to clinically relevant dose levels.",

author = "Skyt, {Peter Sandegaard} and Jensen, {Grethe Vestergaard} and Wahlstedt, {Isak Hannes} and Petersen, {J{\o}rgen Breede Baltzer} and Muren, {Ludvig Paul} and Pedersen, {Jan Skov} and Peter Balling",

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journal = "R S C Advances",

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Investigation of nanoscale structures by small-angle X-ray scattering in a radiochromic dosimeter. / Skyt, Peter Sandegaard; Jensen, Grethe Vestergaard; Wahlstedt, Isak Hannes et al.
I: R S C Advances, Bind 4, Nr. 18, 20.02.2014, s. 9152-9159.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

TY - JOUR

T1 - Investigation of nanoscale structures by small-angle X-ray scattering in a radiochromic dosimeter

AU - Skyt, Peter Sandegaard

AU - Jensen, Grethe Vestergaard

AU - Wahlstedt, Isak Hannes

AU - Petersen, Jørgen Breede Baltzer

AU - Muren, Ludvig Paul

AU - Pedersen, Jan Skov

AU - Balling, Peter

PY - 2014/2/20

Y1 - 2014/2/20

N2 - This study examines the nanoscale structures in a radiochromic dosimeter that was based on leuco-malachite-green dye and the surfactant sodium dodecyl sulfate (SDS) suspended in a gelatin matrix. Small-angle X-ray scattering was used to investigate the structures of a range of compositions of the dosimeter. When omitting gelatin, ellipsoidal micelles of SDS were formed with a core radius near 15 Å, an eccentricity of 1.6, and a head-group shell thickness near 7 Å. Gelatin significantly changed the micelles to a cylindrical shape with around three times lower core radius and four times larger shell thickness, which shows that the gelatin is present in the shell and the outer part of the core. Insight into the detailed structure might help to improve the dosimeter performance and increase the dose response to clinically relevant dose levels.

AB - This study examines the nanoscale structures in a radiochromic dosimeter that was based on leuco-malachite-green dye and the surfactant sodium dodecyl sulfate (SDS) suspended in a gelatin matrix. Small-angle X-ray scattering was used to investigate the structures of a range of compositions of the dosimeter. When omitting gelatin, ellipsoidal micelles of SDS were formed with a core radius near 15 Å, an eccentricity of 1.6, and a head-group shell thickness near 7 Å. Gelatin significantly changed the micelles to a cylindrical shape with around three times lower core radius and four times larger shell thickness, which shows that the gelatin is present in the shell and the outer part of the core. Insight into the detailed structure might help to improve the dosimeter performance and increase the dose response to clinically relevant dose levels.

U2 - 10.1039/c3ra46605a

DO - 10.1039/c3ra46605a

M3 - Journal article

AN - SCOPUS:84893937696

SN - 2046-2069

VL - 4

SP - 9152

EP - 9159

JO - R S C Advances

JF - R S C Advances

IS - 18

ER -

Investigation of nanoscale structures by small-angle X-ray scattering in a radiochromic dosimeter

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