Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Roy Vergis
  • ,
  • Catherine M Corbishley
  • ,
  • Andrew R Norman
  • ,
  • Jaclyn Bartlett
  • ,
  • Sameer Jhavar
  • ,
  • Michael Borre
  • Sara Heebøll
  • Alan Horwich
  • ,
  • Robert Huddart
  • ,
  • Vincent Khoo
  • ,
  • Ros Eeles
  • ,
  • Colin Cooper
  • ,
  • Matthew Sydes
  • ,
  • David Dearnaley
  • ,
  • Chris Parker
Expression of intrinsic markers of tumour hypoxia and angiogenesis are important predictors of radiotherapeutic, and possibly surgical, outcome in several cancers. Extent of tumour hypoxia in localised prostate cancer is comparable to that in other cancers, but few data exist on the association of extent of tumour hypoxia with treatment outcome. We aimed to study the predictive value of intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer, both in patients treated with radiotherapy and in those treated surgically.
OriginalsprogEngelsk
TidsskriftThe Lancet Oncology
Vol/bind9
Nummer4
Sider (fra-til)342-51
Antal sider10
DOI
StatusUdgivet - 2008

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