Interventions to Prevent Sperm DNA Damage Effects on Reproduction

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DOI

  • Sandro C. Esteves, ANDROFERT, Androl & Human Reprod Clin, Referral Ctr Male Reprod, Univ Campinas UNICAMP, Universidade Estadual de Campinas, Dept Surg, Div Urol

Excessive oxidation and antioxidant imbalance resulting from several conditions may cause sperm DNA damage, which, in turn, affect male fertility, both natural and assisted. Sperm DNA damage transferred to the embryo might also affect the health of offspring. Several conditions associated with excessive oxidative stress are modifiable by the use of specific treatments, lifestyle changes, and averting exposure to environmental/occupational toxicants. Here, we discuss the strategies to reduce sperm DNA damage with a focus on clinical and surgical interventions.

OriginalsprogEngelsk
TitelGenetic Damage in Human Spermatozoa
RedaktørerE Baldi, M Muratori
Antal sider30
ForlagSpringer
Udgivelsesår2019
Sider119-148
ISBN (trykt)978-3-030-21663-4
DOI
StatusUdgivet - 2019
SerietitelAdvances in Experimental Medicine and Biology
Vol/bind1166
ISSN0065-2598

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