International benchmarking in type 1 diabetes: Large difference in childhood HbA1c between eight high-income countries but similar rise during adolescence—A quality registry study

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DOI

  • Johan Anderzén, Ryhov County Hospital
  • ,
  • Julia M. Hermann, Ulm University, German Center for Diabetes Research (DZD)
  • ,
  • Ulf Samuelsson, Linköping University
  • ,
  • Dimitrios Charalampopoulos, University College London
  • ,
  • Jannet Svensson, Københavns Universitet
  • ,
  • Torild Skrivarhaug, University of Oslo
  • ,
  • Elke Fröhlich-Reiterer, Medical University of Graz
  • ,
  • David M. Maahs, Division of Pediatric Endocrinology and Stanford Diabetes Research Center
  • ,
  • Karin Akesson, Ryhov County Hospital, Linköping University
  • ,
  • Thomas Kapellen, Leipzig University
  • ,
  • Maria Fritsch, Medical University of Vienna
  • ,
  • Niels H. Birkebæk
  • Ann K. Drivvoll, University of Oslo
  • ,
  • Kellee Miller, Jaeb Center for Health Research
  • ,
  • Terence Stephenson, University College London
  • ,
  • Sabine E. Hofer, Innsbruck Medical University
  • ,
  • Siri Fredheim, Københavns Universitet
  • ,
  • Siv J. Kummernes, University of Oslo
  • ,
  • Nicole Foster, Jaeb Center for Health Research
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  • Rakesh Amin, University College London
  • ,
  • Dörte Hilgard, Pediatric Practice
  • ,
  • Birgit Rami-Merhar, Medical University of Vienna
  • ,
  • Knut Dahl-Jørgensen, University of Oslo
  • ,
  • Mark Clements, Children's Mercy Hospitals and Clinics, University of Missouri at Kansas City, University of Kansas
  • ,
  • Ragnar Hanas, University of Gothenburg
  • ,
  • Reinhard W. Holl, Ulm University, German Center for Diabetes Research (DZD)
  • ,
  • Justin T. Warner, Cardiff & Vale University Health Board

Objectives: To identify differences and similarities in HbA1c levels and patterns regarding age and gender in eight high-income countries. Subjects: 66 071 children and adolescents below18 years of age with type 1 diabetes for at least 3 months and at least one HbA1c measurement during the study period. Methods: Pediatric Diabetes Quality Registry data from Austria, Denmark, England, Germany, Norway, Sweden, the United States, and Wales were collected between 2013 and 2014. HbA1c, gender, age, and duration were used in the analysis. Results: Distribution of gender and age groups was similar in the eight participating countries. The mean HbA1c varied from 60 to 73 mmol/mol (7.6%-8.8%) between the countries. The increase in HbA1c between the youngest (0-9 years) to the oldest (15-17 years) age group was close to 8 mmol/mol (0.7%) in all countries (P <.001). Females had a 1 mmol/mol (0.1%) higher mean HbA1c than boys (P <.001) in seven out of eight countries. Conclusions: In spite of large differences in the mean HbA1c between countries, a remarkable similarity in the increase of HbA1c from childhood to adolescence was found.

OriginalsprogEngelsk
TidsskriftPediatric Diabetes
Vol/bind21
Nummer4
Sider (fra-til)621-627
Antal sider7
ISSN1399-543X
DOI
StatusUdgivet - 2020

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