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Integrative Genomic Analysis of Complex traits

Publikation: Bog/antologi/afhandling/rapportPh.d.-afhandlingForskning

  • Ali Reza Ehsani, Danmark
In the last decade rapid development in biotechnologies has made it possible to extract extensive information about practically all levels of biological organization. An ever-increasing number of studies are reporting miltilayered datasets on the entire DNA sequence, transceroption, protein expression, and metabolite abundance of more and more populations in a multitude of invironments. However, a solid model for including all of this complex information in one analysis, to disentangle genetic variation and the underlying genetic architecture of complex traits and diseases, has not yet been proposed. This thesis introduced a novel way to integrate such huge data sets in an efficient and informative procedure to dissect the comæexity of obesity related traits (e.g. body wight, body fat, feed intake, etc) and map the flow from DNA through RNA ending with individual phenotypes.
OriginalsprogEngelsk
ForlagAarhus University, Faculty of Science and Technology
Antal sider87
ISBN (Trykt)978-87-92936-72-1
Rekvirerende organGraduate School of Science and Technology
StatusUdgivet - 6 jun. 2013

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