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Insulin treatment of the insulin-dependent diabetic patient undergoing minor surgery. Continuous intravenous infusion compared with subcutaneous administration

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Insulin treatment of the insulin-dependent diabetic patient undergoing minor surgery. Continuous intravenous infusion compared with subcutaneous administration. / Christiansen, C L; Schurizek, B A; Malling, B; Knudsen, L; Alberti, K G; Hermansen, K.

I: Anaesthesia, Bind 43, Nr. 7, 07.1988, s. 533-7.

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@article{57a470cf41aa4bacb162f6112b968fb0,
title = "Insulin treatment of the insulin-dependent diabetic patient undergoing minor surgery. Continuous intravenous infusion compared with subcutaneous administration",
abstract = "In a prospective randomised study in 20 insulin-dependent diabetics who had minor surgery under general anaesthesia we compared the metabolic responses to intravenous glucose-insulin-potassium infusion with those who had conventional subcutaneous insulin administration. The former treatment resulted in lower blood glucose levels both during the infusion period (p less than 0.05) as well as the entire observation period (operative, first and second postoperative days; p less than 0.01). More blood glucose values were within the intended range of 5 to 10 mmol/litre in the glucose-insulin-potassium as compared to the conventional group (48% versus 24%; p less than 0.01). The levels of lactate, 3-hydroxybutyrate, glycerol, alanine, glucagon, insulin and growth hormone did not differ between the two groups. The infusion regimen resulted in better glycaemic control both peri-and postoperatively than the conventional subcutaneous insulin regimen in insulin-dependent diabetic patients who have minor surgery.",
keywords = "Adult, Aged, Blood Glucose, Diabetes Mellitus, Type 1, Female, Glucose, Humans, Infusions, Intravenous, Injections, Subcutaneous, Insulin, Male, Middle Aged, Minor Surgical Procedures, Potassium, Prospective Studies, Random Allocation, Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't",
author = "Christiansen, {C L} and Schurizek, {B A} and B Malling and L Knudsen and Alberti, {K G} and K Hermansen",
year = "1988",
month = jul,
language = "English",
volume = "43",
pages = "533--7",
journal = "Anaesthesia",
issn = "0003-2409",
publisher = "Wiley-Blackwell Publishing Ltd.",
number = "7",

}

RIS

TY - JOUR

T1 - Insulin treatment of the insulin-dependent diabetic patient undergoing minor surgery. Continuous intravenous infusion compared with subcutaneous administration

AU - Christiansen, C L

AU - Schurizek, B A

AU - Malling, B

AU - Knudsen, L

AU - Alberti, K G

AU - Hermansen, K

PY - 1988/7

Y1 - 1988/7

N2 - In a prospective randomised study in 20 insulin-dependent diabetics who had minor surgery under general anaesthesia we compared the metabolic responses to intravenous glucose-insulin-potassium infusion with those who had conventional subcutaneous insulin administration. The former treatment resulted in lower blood glucose levels both during the infusion period (p less than 0.05) as well as the entire observation period (operative, first and second postoperative days; p less than 0.01). More blood glucose values were within the intended range of 5 to 10 mmol/litre in the glucose-insulin-potassium as compared to the conventional group (48% versus 24%; p less than 0.01). The levels of lactate, 3-hydroxybutyrate, glycerol, alanine, glucagon, insulin and growth hormone did not differ between the two groups. The infusion regimen resulted in better glycaemic control both peri-and postoperatively than the conventional subcutaneous insulin regimen in insulin-dependent diabetic patients who have minor surgery.

AB - In a prospective randomised study in 20 insulin-dependent diabetics who had minor surgery under general anaesthesia we compared the metabolic responses to intravenous glucose-insulin-potassium infusion with those who had conventional subcutaneous insulin administration. The former treatment resulted in lower blood glucose levels both during the infusion period (p less than 0.05) as well as the entire observation period (operative, first and second postoperative days; p less than 0.01). More blood glucose values were within the intended range of 5 to 10 mmol/litre in the glucose-insulin-potassium as compared to the conventional group (48% versus 24%; p less than 0.01). The levels of lactate, 3-hydroxybutyrate, glycerol, alanine, glucagon, insulin and growth hormone did not differ between the two groups. The infusion regimen resulted in better glycaemic control both peri-and postoperatively than the conventional subcutaneous insulin regimen in insulin-dependent diabetic patients who have minor surgery.

KW - Adult

KW - Aged

KW - Blood Glucose

KW - Diabetes Mellitus, Type 1

KW - Female

KW - Glucose

KW - Humans

KW - Infusions, Intravenous

KW - Injections, Subcutaneous

KW - Insulin

KW - Male

KW - Middle Aged

KW - Minor Surgical Procedures

KW - Potassium

KW - Prospective Studies

KW - Random Allocation

KW - Clinical Trial

KW - Comparative Study

KW - Journal Article

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

M3 - Journal article

C2 - 3046411

VL - 43

SP - 533

EP - 537

JO - Anaesthesia

JF - Anaesthesia

SN - 0003-2409

IS - 7

ER -