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Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study. / Jakszyn, P; Cayssials, V; Buckland, G; Perez-Cornago, A; Weiderpass, E; Boeing, H; Bergmann, M M; Vulcan, A; Ohlsson, B; Masala, G; Cross, A J; Riboli, E; Ricceri, F; Dahm, C; Nyvang, D; Katzke, V A; Kühns, T; Kyrø, C; Tjønneland, A; Ward, H A; Tsilidis, K K; Skeie, G; Sieri, S; Sanchez, M J; Huerta, J M; Amiano, P; Lasheras, C; Ardanaz, E; Mahamat-Saleh, Y; Boutron-Ruault, M C; Carbonnel, F; Panico, S; Peppa, E; Trichopoulou, A; Karakatsani, A; Tumino, R; Vermeulen, R; Jenab, M; Gunter, M; Agudo, A.

I: International Journal of Cancer, Bind 147, Nr. 4, 2020, s. 1027-1039.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Jakszyn, P, Cayssials, V, Buckland, G, Perez-Cornago, A, Weiderpass, E, Boeing, H, Bergmann, MM, Vulcan, A, Ohlsson, B, Masala, G, Cross, AJ, Riboli, E, Ricceri, F, Dahm, C, Nyvang, D, Katzke, VA, Kühns, T, Kyrø, C, Tjønneland, A, Ward, HA, Tsilidis, KK, Skeie, G, Sieri, S, Sanchez, MJ, Huerta, JM, Amiano, P, Lasheras, C, Ardanaz, E, Mahamat-Saleh, Y, Boutron-Ruault, MC, Carbonnel, F, Panico, S, Peppa, E, Trichopoulou, A, Karakatsani, A, Tumino, R, Vermeulen, R, Jenab, M, Gunter, M & Agudo, A 2020, 'Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study', International Journal of Cancer, bind 147, nr. 4, s. 1027-1039. https://doi.org/10.1002/ijc.32870

APA

Jakszyn, P., Cayssials, V., Buckland, G., Perez-Cornago, A., Weiderpass, E., Boeing, H., Bergmann, M. M., Vulcan, A., Ohlsson, B., Masala, G., Cross, A. J., Riboli, E., Ricceri, F., Dahm, C., Nyvang, D., Katzke, V. A., Kühns, T., Kyrø, C., Tjønneland, A., ... Agudo, A. (2020). Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study. International Journal of Cancer, 147(4), 1027-1039. https://doi.org/10.1002/ijc.32870

CBE

Jakszyn P, Cayssials V, Buckland G, Perez-Cornago A, Weiderpass E, Boeing H, Bergmann MM, Vulcan A, Ohlsson B, Masala G, Cross AJ, Riboli E, Ricceri F, Dahm C, Nyvang D, Katzke VA, Kühns T, Kyrø C, Tjønneland A, Ward HA, Tsilidis KK, Skeie G, Sieri S, Sanchez MJ, Huerta JM, Amiano P, Lasheras C, Ardanaz E, Mahamat-Saleh Y, Boutron-Ruault MC, Carbonnel F, Panico S, Peppa E, Trichopoulou A, Karakatsani A, Tumino R, Vermeulen R, Jenab M, Gunter M, Agudo A. 2020. Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study. International Journal of Cancer. 147(4):1027-1039. https://doi.org/10.1002/ijc.32870

MLA

Vancouver

Jakszyn P, Cayssials V, Buckland G, Perez-Cornago A, Weiderpass E, Boeing H o.a. Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study. International Journal of Cancer. 2020;147(4):1027-1039. https://doi.org/10.1002/ijc.32870

Author

Jakszyn, P ; Cayssials, V ; Buckland, G ; Perez-Cornago, A ; Weiderpass, E ; Boeing, H ; Bergmann, M M ; Vulcan, A ; Ohlsson, B ; Masala, G ; Cross, A J ; Riboli, E ; Ricceri, F ; Dahm, C ; Nyvang, D ; Katzke, V A ; Kühns, T ; Kyrø, C ; Tjønneland, A ; Ward, H A ; Tsilidis, K K ; Skeie, G ; Sieri, S ; Sanchez, M J ; Huerta, J M ; Amiano, P ; Lasheras, C ; Ardanaz, E ; Mahamat-Saleh, Y ; Boutron-Ruault, M C ; Carbonnel, F ; Panico, S ; Peppa, E ; Trichopoulou, A ; Karakatsani, A ; Tumino, R ; Vermeulen, R ; Jenab, M ; Gunter, M ; Agudo, A. / Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study. I: International Journal of Cancer. 2020 ; Bind 147, Nr. 4. s. 1027-1039.

Bibtex

@article{612896c99f9f48b1b1dafac6ab87d421,
title = "Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study",
abstract = "Pro-inflammatory diets are associated with risk of developing colorectal cancer (CRC), however inconsistencies exist in subsite- and sex-specific associations. The relationship between CRC and combined lifestyle-related factors that contribute towards a low-grade inflammatory profile has not yet been explored. We examined the association between the dietary inflammatory potential and an inflammatory profile and CRC risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. This cohort included 476,160 participants followed-up of 14 years and 5,991 incident CRC cases (3,897 colon and 2,094 rectal tumours). Dietary inflammatory potential was estimated using an Inflammatory Score of the Diet (ISD). An Inflammatory Profile Score (IPS) was constructed, incorporating the ISD, physical activity level and abdominal obesity. The associations between the ISD and CRC and IPS and CRC were assessed using multivariable regression models. More pro- inflammatory diets were related to a higher CRC risk, particularly for colon cancer; Hazar Ratio (HR) for highest versus lowest ISD quartile was 1.15 (95% confidence interval (CI) 1.04-1.27) for CRC, 1.24 (95% CI 1.09-1.41) for colon cancer and 0.99 (95% CI 0.83-1.17) for rectal cancer. Associations were more pronounced in men and not significant in women. The IPS was associated with CRC risk, particularly colon cancer among men; HRs for the highest versus lowest IPS were 1.62 (95% CI 1.31- 2.01) for colon cancer overall and 2.11 (95% CI 1.50-2.97) for colon cancer in men. This study shows that more pro-inflammatory diets and a more inflammatory profile are associated with higher risk of CRC, principally colon cancer and in men. This article is protected by copyright. All rights reserved.",
keywords = "Europe, inflammatory potential of the diet, association, colorectal cancer, epidemiology, prospective cohort",
author = "P Jakszyn and V Cayssials and G Buckland and A Perez-Cornago and E Weiderpass and H Boeing and Bergmann, {M M} and A Vulcan and B Ohlsson and G Masala and Cross, {A J} and E Riboli and F Ricceri and C Dahm and D Nyvang and Katzke, {V A} and T K{\"u}hns and C Kyr{\o} and A Tj{\o}nneland and Ward, {H A} and Tsilidis, {K K} and G Skeie and S Sieri and Sanchez, {M J} and Huerta, {J M} and P Amiano and C Lasheras and E Ardanaz and Y Mahamat-Saleh and Boutron-Ruault, {M C} and F Carbonnel and S Panico and E Peppa and A Trichopoulou and A Karakatsani and R Tumino and R Vermeulen and M Jenab and M Gunter and A Agudo",
note = "This article is protected by copyright. All rights reserved.",
year = "2020",
doi = "10.1002/ijc.32870",
language = "English",
volume = "147",
pages = "1027--1039",
journal = "International Journal of Cancer",
issn = "0020-7136",
publisher = "JohnWiley & Sons, Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

AU - Jakszyn, P

AU - Cayssials, V

AU - Buckland, G

AU - Perez-Cornago, A

AU - Weiderpass, E

AU - Boeing, H

AU - Bergmann, M M

AU - Vulcan, A

AU - Ohlsson, B

AU - Masala, G

AU - Cross, A J

AU - Riboli, E

AU - Ricceri, F

AU - Dahm, C

AU - Nyvang, D

AU - Katzke, V A

AU - Kühns, T

AU - Kyrø, C

AU - Tjønneland, A

AU - Ward, H A

AU - Tsilidis, K K

AU - Skeie, G

AU - Sieri, S

AU - Sanchez, M J

AU - Huerta, J M

AU - Amiano, P

AU - Lasheras, C

AU - Ardanaz, E

AU - Mahamat-Saleh, Y

AU - Boutron-Ruault, M C

AU - Carbonnel, F

AU - Panico, S

AU - Peppa, E

AU - Trichopoulou, A

AU - Karakatsani, A

AU - Tumino, R

AU - Vermeulen, R

AU - Jenab, M

AU - Gunter, M

AU - Agudo, A

N1 - This article is protected by copyright. All rights reserved.

PY - 2020

Y1 - 2020

N2 - Pro-inflammatory diets are associated with risk of developing colorectal cancer (CRC), however inconsistencies exist in subsite- and sex-specific associations. The relationship between CRC and combined lifestyle-related factors that contribute towards a low-grade inflammatory profile has not yet been explored. We examined the association between the dietary inflammatory potential and an inflammatory profile and CRC risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. This cohort included 476,160 participants followed-up of 14 years and 5,991 incident CRC cases (3,897 colon and 2,094 rectal tumours). Dietary inflammatory potential was estimated using an Inflammatory Score of the Diet (ISD). An Inflammatory Profile Score (IPS) was constructed, incorporating the ISD, physical activity level and abdominal obesity. The associations between the ISD and CRC and IPS and CRC were assessed using multivariable regression models. More pro- inflammatory diets were related to a higher CRC risk, particularly for colon cancer; Hazar Ratio (HR) for highest versus lowest ISD quartile was 1.15 (95% confidence interval (CI) 1.04-1.27) for CRC, 1.24 (95% CI 1.09-1.41) for colon cancer and 0.99 (95% CI 0.83-1.17) for rectal cancer. Associations were more pronounced in men and not significant in women. The IPS was associated with CRC risk, particularly colon cancer among men; HRs for the highest versus lowest IPS were 1.62 (95% CI 1.31- 2.01) for colon cancer overall and 2.11 (95% CI 1.50-2.97) for colon cancer in men. This study shows that more pro-inflammatory diets and a more inflammatory profile are associated with higher risk of CRC, principally colon cancer and in men. This article is protected by copyright. All rights reserved.

AB - Pro-inflammatory diets are associated with risk of developing colorectal cancer (CRC), however inconsistencies exist in subsite- and sex-specific associations. The relationship between CRC and combined lifestyle-related factors that contribute towards a low-grade inflammatory profile has not yet been explored. We examined the association between the dietary inflammatory potential and an inflammatory profile and CRC risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. This cohort included 476,160 participants followed-up of 14 years and 5,991 incident CRC cases (3,897 colon and 2,094 rectal tumours). Dietary inflammatory potential was estimated using an Inflammatory Score of the Diet (ISD). An Inflammatory Profile Score (IPS) was constructed, incorporating the ISD, physical activity level and abdominal obesity. The associations between the ISD and CRC and IPS and CRC were assessed using multivariable regression models. More pro- inflammatory diets were related to a higher CRC risk, particularly for colon cancer; Hazar Ratio (HR) for highest versus lowest ISD quartile was 1.15 (95% confidence interval (CI) 1.04-1.27) for CRC, 1.24 (95% CI 1.09-1.41) for colon cancer and 0.99 (95% CI 0.83-1.17) for rectal cancer. Associations were more pronounced in men and not significant in women. The IPS was associated with CRC risk, particularly colon cancer among men; HRs for the highest versus lowest IPS were 1.62 (95% CI 1.31- 2.01) for colon cancer overall and 2.11 (95% CI 1.50-2.97) for colon cancer in men. This study shows that more pro-inflammatory diets and a more inflammatory profile are associated with higher risk of CRC, principally colon cancer and in men. This article is protected by copyright. All rights reserved.

KW - Europe

KW - inflammatory potential of the diet

KW - association

KW - colorectal cancer

KW - epidemiology

KW - prospective cohort

UR - http://www.scopus.com/inward/record.url?scp=85078900968&partnerID=8YFLogxK

U2 - 10.1002/ijc.32870

DO - 10.1002/ijc.32870

M3 - Journal article

C2 - 31945199

VL - 147

SP - 1027

EP - 1039

JO - International Journal of Cancer

JF - International Journal of Cancer

SN - 0020-7136

IS - 4

ER -