Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2

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Standard

Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2. / Ekman, G; Uldbjerg, N; Malmström, A; Ulmsten, U.

I: Gynecologic and Obstetric Investigation, Bind 16, Nr. 5, 1983, s. 292-8.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Ekman, G, Uldbjerg, N, Malmström, A & Ulmsten, U 1983, 'Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2', Gynecologic and Obstetric Investigation, bind 16, nr. 5, s. 292-8.

APA

Ekman, G., Uldbjerg, N., Malmström, A., & Ulmsten, U. (1983). Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2. Gynecologic and Obstetric Investigation, 16(5), 292-8.

CBE

Ekman G, Uldbjerg N, Malmström A, Ulmsten U. 1983. Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2. Gynecologic and Obstetric Investigation. 16(5):292-8.

MLA

Vancouver

Ekman G, Uldbjerg N, Malmström A, Ulmsten U. Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2. Gynecologic and Obstetric Investigation. 1983;16(5):292-8.

Author

Ekman, G ; Uldbjerg, N ; Malmström, A ; Ulmsten, U. / Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2. I: Gynecologic and Obstetric Investigation. 1983 ; Bind 16, Nr. 5. s. 292-8.

Bibtex

@article{7a6eaaa071b011df8c1a000ea68e967b,
title = "Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2",
abstract = "Cervical biopsies obtained from 7 patients immediately following parturition induced by intracervical application of 0.5 mg prostaglandin E2 (PGE2) in viscous gel were compared with similar biopsies from 11 spontaneously delivered women. A DNP-peptide hydrolytic activity (collagenase) was significantly increased in cervical tissue from the PGE2-induced patients compared with controls. In patients with prompt clinical response, the increase was nearly twofold. No differences were found in the concentrations of water, sulfated glycosaminoglycans, hyaluronic acid, hydroxyproline or leukocyte elastase. Thus, PGE2-induced cervical priming seems to be associated with an increased collagenolytic activity.",
keywords = "Adult, Cervix Uteri, Dinoprostone, Female, Glycosaminoglycans, Humans, Hyaluronic Acid, Hydroxyproline, Labor, Induced, Male, Microbial Collagenase, Pregnancy, Prostaglandins E",
author = "G Ekman and N Uldbjerg and A Malmstr{\"o}m and U Ulmsten",
year = "1983",
language = "English",
volume = "16",
pages = "292--8",
journal = "Gynecologic and Obstetric Investigation",
issn = "0378-7346",
publisher = "S. Karger AG",
number = "5",

}

RIS

TY - JOUR

T1 - Increased postpartum collagenolytic activity in cervical connective tissue from women treated with prostaglandin E2

AU - Ekman, G

AU - Uldbjerg, N

AU - Malmström, A

AU - Ulmsten, U

PY - 1983

Y1 - 1983

N2 - Cervical biopsies obtained from 7 patients immediately following parturition induced by intracervical application of 0.5 mg prostaglandin E2 (PGE2) in viscous gel were compared with similar biopsies from 11 spontaneously delivered women. A DNP-peptide hydrolytic activity (collagenase) was significantly increased in cervical tissue from the PGE2-induced patients compared with controls. In patients with prompt clinical response, the increase was nearly twofold. No differences were found in the concentrations of water, sulfated glycosaminoglycans, hyaluronic acid, hydroxyproline or leukocyte elastase. Thus, PGE2-induced cervical priming seems to be associated with an increased collagenolytic activity.

AB - Cervical biopsies obtained from 7 patients immediately following parturition induced by intracervical application of 0.5 mg prostaglandin E2 (PGE2) in viscous gel were compared with similar biopsies from 11 spontaneously delivered women. A DNP-peptide hydrolytic activity (collagenase) was significantly increased in cervical tissue from the PGE2-induced patients compared with controls. In patients with prompt clinical response, the increase was nearly twofold. No differences were found in the concentrations of water, sulfated glycosaminoglycans, hyaluronic acid, hydroxyproline or leukocyte elastase. Thus, PGE2-induced cervical priming seems to be associated with an increased collagenolytic activity.

KW - Adult

KW - Cervix Uteri

KW - Dinoprostone

KW - Female

KW - Glycosaminoglycans

KW - Humans

KW - Hyaluronic Acid

KW - Hydroxyproline

KW - Labor, Induced

KW - Male

KW - Microbial Collagenase

KW - Pregnancy

KW - Prostaglandins E

M3 - Journal article

C2 - 6315547

VL - 16

SP - 292

EP - 298

JO - Gynecologic and Obstetric Investigation

JF - Gynecologic and Obstetric Investigation

SN - 0378-7346

IS - 5

ER -