TY - JOUR
T1 - Impella CP Implantation during Cardiopulmonary Resuscitation for Cardiac Arrest
T2 - A Multicenter Experience
AU - Panagides, Vassili
AU - Vase, Henrik
AU - Shah, Sachin P
AU - Basir, Mir B
AU - Mancini, Julien
AU - Kamran, Hayaan
AU - Batra, Supria
AU - Laine, Marc
AU - Eiskjær, Hans
AU - Christensen, Steffen
AU - Karami, Mina
AU - Paganelli, Franck
AU - Henriques, Jose P S
AU - Bonello, Laurent
PY - 2021/1/2
Y1 - 2021/1/2
N2 - Background: Impella CP is a left ventricular pump which may serve as a circulatory support during cardiopulmonary resuscitation (CPR) for cardiac arrest (CA). Nevertheless, the survival rate and factors associated with survival in patients undergoing Impella insertion during CPR for CA are unknown. Methods: We performed a retrospective multicenter international registry of patients undergoing Impella insertion during on-going CPR for in-or out-of-hospital CA. We recorded immediate and 30-day survival with and without neurologic impairment using the cerebral performance category score and evaluated the factors associated with survival. Results: Thirty-five patients had an Impella CP implanted during CPR for CA. Refractory ventricular arrhythmias were the most frequent initial rhythm (65.7%). In total, 65.7% of patients immediately survived. At 30 days, 45.7% of patients were still alive. The 30-day survival rate without neurological impairment was 37.1%. In univariate analysis, survival was associated with both an age < 75 years and a time from arrest to CPR ≤ 5 min (p = 0.035 and p = 0.008, respectively). Conclusions: In our multicenter registry, Impella CP insertion during ongoing CPR for CA was associated with a 37.1% rate of 30-day survival without neurological impairment. The factors associated with survival were a young age and a time from arrest to CPR ≤ 5 min.
AB - Background: Impella CP is a left ventricular pump which may serve as a circulatory support during cardiopulmonary resuscitation (CPR) for cardiac arrest (CA). Nevertheless, the survival rate and factors associated with survival in patients undergoing Impella insertion during CPR for CA are unknown. Methods: We performed a retrospective multicenter international registry of patients undergoing Impella insertion during on-going CPR for in-or out-of-hospital CA. We recorded immediate and 30-day survival with and without neurologic impairment using the cerebral performance category score and evaluated the factors associated with survival. Results: Thirty-five patients had an Impella CP implanted during CPR for CA. Refractory ventricular arrhythmias were the most frequent initial rhythm (65.7%). In total, 65.7% of patients immediately survived. At 30 days, 45.7% of patients were still alive. The 30-day survival rate without neurological impairment was 37.1%. In univariate analysis, survival was associated with both an age < 75 years and a time from arrest to CPR ≤ 5 min (p = 0.035 and p = 0.008, respectively). Conclusions: In our multicenter registry, Impella CP insertion during ongoing CPR for CA was associated with a 37.1% rate of 30-day survival without neurological impairment. The factors associated with survival were a young age and a time from arrest to CPR ≤ 5 min.
KW - Cardiac arrest
KW - Cardiopulmonary resuscitation
KW - Hemodynamic support device
KW - Impella
KW - Refractory cardiac arrest
UR - http://www.scopus.com/inward/record.url?scp=85106679314&partnerID=8YFLogxK
U2 - 10.3390/jcm10020339
DO - 10.3390/jcm10020339
M3 - Journal article
C2 - 33477532
SN - 2077-0383
VL - 10
SP - 1
EP - 10
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 2
M1 - 339
ER -