TY - JOUR

T1 - Impact of oral motor task training on corticomotor pathways and diadochokinetic rates in young healthy participants

AU - Boscato, Noéli

AU - Hayakawa, Hidetoshi

AU - Iida, Takashi

AU - Costa, Yuri M.

AU - Kothari, Simple Futarmal

AU - Kothari, Mohit

AU - Svensson, Peter

PY - 2022/9

Y1 - 2022/9

N2 - Background: Studies addressing the training-induced neuroplasticity and interrelationships of the lip, masseter, and tongue motor representations in the human motor cortex using single syllable repetition are lacking. Objective: This study investigated the impact of a repeated training in a novel PaTaKa diadochokinetic (DDK) orofacial motor task (OMT) on corticomotor control of the lips, masseter, and tongue muscles in young healthy participants. Methods: A total of 22 young healthy volunteers performed 3 consecutive days of training in an OMT. Transcranial magnetic stimulation was applied to elicit motor evoked potentials (MEPs) from the lip, masseter, tongue, and first dorsal interosseous (FDI, internal control) muscles. MEPs were assessed by stimulus–response curves and corticomotor mapping at baseline and after OMT. The DDK rate from PaTaKa single syllable repetition and numeric rating scale (NRS) scores were also obtained at baseline and immediately after each OMT. Repeated-measures analysis of variance was used to detect differences at a significance level of 5%. Results: There was a significant effect of OMT and stimulus intensity on the lips, masseter, and tongue MEPs compared to baseline (p <.001), but not FDI MEPs (p >.05). OMT increased corticomotor topographic maps area (p <.001), and DDK rates (p <.01). Conclusion: Our findings suggest that 3 consecutive days of a repeated PaTaKa training in an OMT can induce neuroplastic changes in the corticomotor pathways of orofacial muscles, and it may be related to mechanisms underlying the improvement of orofacial fine motor skills due to short-term training. The clinical utility should now be investigated.

AB - Background: Studies addressing the training-induced neuroplasticity and interrelationships of the lip, masseter, and tongue motor representations in the human motor cortex using single syllable repetition are lacking. Objective: This study investigated the impact of a repeated training in a novel PaTaKa diadochokinetic (DDK) orofacial motor task (OMT) on corticomotor control of the lips, masseter, and tongue muscles in young healthy participants. Methods: A total of 22 young healthy volunteers performed 3 consecutive days of training in an OMT. Transcranial magnetic stimulation was applied to elicit motor evoked potentials (MEPs) from the lip, masseter, tongue, and first dorsal interosseous (FDI, internal control) muscles. MEPs were assessed by stimulus–response curves and corticomotor mapping at baseline and after OMT. The DDK rate from PaTaKa single syllable repetition and numeric rating scale (NRS) scores were also obtained at baseline and immediately after each OMT. Repeated-measures analysis of variance was used to detect differences at a significance level of 5%. Results: There was a significant effect of OMT and stimulus intensity on the lips, masseter, and tongue MEPs compared to baseline (p <.001), but not FDI MEPs (p >.05). OMT increased corticomotor topographic maps area (p <.001), and DDK rates (p <.01). Conclusion: Our findings suggest that 3 consecutive days of a repeated PaTaKa training in an OMT can induce neuroplastic changes in the corticomotor pathways of orofacial muscles, and it may be related to mechanisms underlying the improvement of orofacial fine motor skills due to short-term training. The clinical utility should now be investigated.

KW - diadochokinetic

KW - language

KW - motor learning

KW - oral function

KW - plasticity

KW - transcranial magnetic stimulation

KW - Humans

KW - Evoked Potentials, Motor/physiology

KW - Healthy Volunteers

KW - Motor Cortex/physiology

KW - Transcranial Magnetic Stimulation

KW - Neuronal Plasticity/physiology

KW - Electromyography

KW - Muscle, Skeletal

UR - http://www.scopus.com/inward/record.url?scp=85133143139&partnerID=8YFLogxK

U2 - 10.1111/joor.13349

DO - 10.1111/joor.13349

M3 - Journal article

C2 - 35722734

VL - 49

SP - 924

EP - 934

JO - Journal of Oral Rehabilitation

JF - Journal of Oral Rehabilitation

SN - 0305-182X

IS - 9

ER -