Imaging Insights on Club Crystallites and Osteoorientations

TY - BOOK

T1 - Imaging Insights on Club Crystallites and Osteoorientations

AU - Christensen, Thorbjørn Erik Køppen

PY - 2023/1/31

Y1 - 2023/1/31

N2 - Nature is a difficult place for life to live, as such biology has devisedmany interesting materials to cope with its harsh environments. Thematerials of nature are often wonderfully complex and intricate,combining the properties of multiple components to create materialsthat can live up to the tasks they are wrought through. Understand-ing bioinorganic materials can provide both an inspiration for futuresynthetic materials and the pathway to improving medical proce-dures when integration with materials such as bone is necessary.My research leading to the present dissertation has focused onthree major topics. Development of analytical methods for analyzingX-ray diffraction data. The bioinorganic material in the stomatopoddactyl club. The mineralized structural matrix of bone.X-ray methods are great for analyzing bioinorganic structures,as they have the penetration power to go through them, and canbe used in multiple different ways to characterize materials. Aspart of this thesis methods have been developed to quickly andeffectively integrate diffraction patterns, and analyze the orientationof crystallites using X-ray diffraction.The dactyl club of the stomatopod encompasses many differentregions, which hold wildly different structures. The work on thedactyl club shows previously unseen details in the impact surface,and that biomineralization occurs earlier than previously thought.Multiple new structures in the dactyl clubs are presented herein.Bone studies forming part of this thesis show that there mineralstructure is orientation dependant in a very small volume of bone,using a 50 nm beamt to examine bone in great detail. Explorations ofthe effect of Sr coatings on osseointegration show that Sr is confinedto the immidiate area surrounding the the implant and that it affectsmultiple crystallite parameters.

AB - Nature is a difficult place for life to live, as such biology has devisedmany interesting materials to cope with its harsh environments. Thematerials of nature are often wonderfully complex and intricate,combining the properties of multiple components to create materialsthat can live up to the tasks they are wrought through. Understand-ing bioinorganic materials can provide both an inspiration for futuresynthetic materials and the pathway to improving medical proce-dures when integration with materials such as bone is necessary.My research leading to the present dissertation has focused onthree major topics. Development of analytical methods for analyzingX-ray diffraction data. The bioinorganic material in the stomatopoddactyl club. The mineralized structural matrix of bone.X-ray methods are great for analyzing bioinorganic structures,as they have the penetration power to go through them, and canbe used in multiple different ways to characterize materials. Aspart of this thesis methods have been developed to quickly andeffectively integrate diffraction patterns, and analyze the orientationof crystallites using X-ray diffraction.The dactyl club of the stomatopod encompasses many differentregions, which hold wildly different structures. The work on thedactyl club shows previously unseen details in the impact surface,and that biomineralization occurs earlier than previously thought.Multiple new structures in the dactyl clubs are presented herein.Bone studies forming part of this thesis show that there mineralstructure is orientation dependant in a very small volume of bone,using a 50 nm beamt to examine bone in great detail. Explorations ofthe effect of Sr coatings on osseointegration show that Sr is confinedto the immidiate area surrounding the the implant and that it affectsmultiple crystallite parameters.

M3 - Ph.D. thesis

BT - Imaging Insights on Club Crystallites and Osteoorientations

ER -