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Imagen del tensor de difusión de la vía corticoespinal y su asociación con el pronóstico del infarto cerebral agudo: Experiencia de una cohorte en México

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DOI

  • Talia Moreno-Andrade, Universidad Autonoma de Nuevo Leon
  • ,
  • Eduardo Garza-Villarreal
  • Alejandro Gonzalez-Aquines, Universidad Autonoma de Nuevo Leon
  • ,
  • Estefania Villarreal-Garza, Universidad Autonoma de Nuevo Leon
  • ,
  • Natalia Lopez-Garza, Universidad Autonoma de Nuevo Leon
  • ,
  • Mario Campos-Coy, Universidad Autonoma de Nuevo Leon
  • ,
  • Guillermo Elizondo-Riojas, Universidad Autonoma de Nuevo Leon
  • ,
  • Fernando Gongora-Rivera, Universidad Autonoma de Nuevo Leon, Universidad Nacional Autónoma de México

Introduction. Magnetic resonance diffusion tensor imaging through the fraction of anisotropy allows evaluation of the integrity of the motor pathways after cerebral infarction. Aims. To correlate the fraction of anisotropy with the clinical scales and the prognosis of cerebral infarction. Subjects and methods. Prospective study of patients with cerebral infarction to compare the fraction of anisotropy in different regions of interest with functional evaluations and with controls free of infarction. A subgroup of subjects with rehabilitation underwent an initial MRI scan and another at three months, with clinical follow-up for six months. Results. Thirty-eight consecutive patients with middle cerebral artery infarction were included. The fraction of anisotropy values were lower in the ipsilateral corticospinal pathway than the fraction of anisotropy of the corticospinal pathway of the controls. The values of the fraction of anisotropy in the ipsilateral corticospinal pathway were associated with the value of the functional scale on admission. Changes in the fraction of anisotropy values between the initial MRI and the scan performed at three months correlated with the score on the functional scale and the modified Rankin scale at three and six months. Conclusions. The value of the fraction of anisotropy in the ipsilateral internal capsule is associated with the presence of a lesion and with its presenting symptoms. Changes in the fraction of anisotropy at three months suggest long-term clinical recovery.

Bidragets oversatte titelDiffusion tensor imaging of the corticospinal pathway and its association with the prognosis of acute cerebral infarction: Experience with a cohort in Mexico
OriginalsprogSpansk
TidsskriftRevista de Neurologia
Vol/bind72
Nummer1
Sider (fra-til)16-22
Antal sider7
ISSN0210-0010
DOI
StatusUdgivet - jan. 2021

    Forskningsområder

  • Cerebral infarction, Diffusion tensor imaging, Fraction of anisotropy, Prognosis, Tractography

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