Hyperthermic tumour-cell devitalization in vivo

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A review of the morphologic, biochemical and clinical effects of hyperthermia on malignant cells indicates the presence of two principally different heat-induced alterations. (1) A 'destructive' lysosomal dependent cytoplasmic reaction dominates the tumour-cell devitalization in vivo, probably influenced by the characteristic tumour cell environment. (2) 'Repressive' nuclear abnormalities may be observed, but seem to be secondary in the in vivo reaction. However, under certain conditions (combined treatment modalities) this nuclear effect may be of importance.
OriginalsprogEngelsk
TidsskriftActa radiologica: therapy, physics, biology
Vol/bind16
Nummer1
Sider (fra-til)1-16
Antal sider16
ISSN0567-8064
StatusUdgivet - maj 1977

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