Human embryonic development after blastomere removal: a time-lapse analysis

Kirstine Kirkegaard; Johnny Juhl Hindkjaer; Hans Jakob Ingerslev

doi:10.1093/humrep/der382

Human embryonic development after blastomere removal: a time-lapse analysis

Kirstine Kirkegaard, Johnny Juhl Hindkjaer, Hans Jakob Ingerslev

Institut for Klinisk Medicin - Kvindesygdomme og Fødsler

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

91 Citationer (Scopus)

Abstract

Blastomere biopsy of human embryos is performed for preimplantation genetic diagnosis (PGD). The impact on further development is largely unexplored, though studies on mice suggest an influence on the hatching process. The objective of this study was to evaluate the effect of blastomere biopsy on early human embryonic development using time-lapse analysis.

Originalsprog	Engelsk
Tidsskrift	Human Reproduction
Vol/bind	27
Nummer	1
Sider (fra-til)	97-105
Antal sider	9
ISSN	0268-1161
DOI	https://doi.org/10.1093/humrep/der382
Status	Udgivet - 2012

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10.1093/humrep/der382

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abstract = "Blastomere biopsy of human embryos is performed for preimplantation genetic diagnosis (PGD). The impact on further development is largely unexplored, though studies on mice suggest an influence on the hatching process. The objective of this study was to evaluate the effect of blastomere biopsy on early human embryonic development using time-lapse analysis.",

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author = "Kirstine Kirkegaard and Hindkjaer, {Johnny Juhl} and Ingerslev, {Hans Jakob}",

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T1 - Human embryonic development after blastomere removal

T2 - a time-lapse analysis

AU - Kirkegaard, Kirstine

AU - Hindkjaer, Johnny Juhl

AU - Ingerslev, Hans Jakob

PY - 2012

Y1 - 2012

N2 - Blastomere biopsy of human embryos is performed for preimplantation genetic diagnosis (PGD). The impact on further development is largely unexplored, though studies on mice suggest an influence on the hatching process. The objective of this study was to evaluate the effect of blastomere biopsy on early human embryonic development using time-lapse analysis.

AB - Blastomere biopsy of human embryos is performed for preimplantation genetic diagnosis (PGD). The impact on further development is largely unexplored, though studies on mice suggest an influence on the hatching process. The objective of this study was to evaluate the effect of blastomere biopsy on early human embryonic development using time-lapse analysis.

KW - Adult

KW - Biopsy

KW - Blastocyst

KW - Blastomeres

KW - Calcium

KW - Case-Control Studies

KW - Female

KW - Fertilization in Vitro

KW - Humans

KW - Magnesium

KW - Preimplantation Diagnosis

KW - Sperm Injections, Intracytoplasmic

KW - Time Factors

KW - Zona Pellucida

U2 - 10.1093/humrep/der382

DO - 10.1093/humrep/der382

M3 - Journal article

C2 - 22081251

SN - 0268-1161

VL - 27

SP - 97

EP - 105

JO - Human Reproduction

JF - Human Reproduction

IS - 1

ER -

Human embryonic development after blastomere removal: a time-lapse analysis

Abstract

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