Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows

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Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows. / Difford, Gareth Frank; Plichta, Damian Rafal; Løvendahl, Peter; Lassen, Jan; Noel, Samantha Joan; Højberg, Ole; Wright, André-Denis G; Zhu, Zhigang; Kristensen, Lise; Nielsen, Henrik Bjørn; Guldbrandtsen, Bernt; Sahana, Goutam.

I: PLOS Genetics, Bind 14, Nr. 10, 12.10.2018, s. e1007580.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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Difford, Gareth Frank ; Plichta, Damian Rafal ; Løvendahl, Peter ; Lassen, Jan ; Noel, Samantha Joan ; Højberg, Ole ; Wright, André-Denis G ; Zhu, Zhigang ; Kristensen, Lise ; Nielsen, Henrik Bjørn ; Guldbrandtsen, Bernt ; Sahana, Goutam. / Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows. I: PLOS Genetics. 2018 ; Bind 14, Nr. 10. s. e1007580.

Bibtex

@article{f6e06555b6644ac3babde4838cd30004,
title = "Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows",
abstract = "Cattle and other ruminants produce large quantities of methane (~110 million metric tonnes per annum), which is a potent greenhouse gas affecting global climate change. Methane (CH4) is a natural by-product of gastro-enteric microbial fermentation of feedstuffs in the rumen and contributes to 6{\%} of total CH4 emissions from anthropogenic-related sources. The extent to which the host genome and rumen microbiome influence CH4 emission is not yet well known. This study confirms individual variation in CH4 production was influenced by individual host (cow) genotype, as well as the host's rumen microbiome composition. Abundance of a small proportion of bacteria and archaea taxa were influenced to a limited extent by the host's genotype and certain taxa were associated with CH4 emissions. However, the cumulative effect of all bacteria and archaea on CH4 production was 13{\%}, the host genetics (heritability) was 21{\%} and the two are largely independent. This study demonstrates variation in CH4 emission is likely not modulated through cow genetic effects on the rumen microbiome. Therefore, the rumen microbiome and cow genome could be targeted independently, by breeding low methane-emitting cows and in parallel, by investigating possible strategies that target changes in the rumen microbiome to reduce CH4 emissions in the cattle industry.",
author = "Difford, {Gareth Frank} and Plichta, {Damian Rafal} and Peter L{\o}vendahl and Jan Lassen and Noel, {Samantha Joan} and Ole H{\o}jberg and Wright, {Andr{\'e}-Denis G} and Zhigang Zhu and Lise Kristensen and Nielsen, {Henrik Bj{\o}rn} and Bernt Guldbrandtsen and Goutam Sahana",
year = "2018",
month = "10",
day = "12",
doi = "10.1371/journal.pgen.1007580",
language = "English",
volume = "14",
pages = "e1007580",
journal = "P L o S Genetics",
issn = "1553-7390",
publisher = "public library of science",
number = "10",

}

RIS

TY - JOUR

T1 - Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows

AU - Difford, Gareth Frank

AU - Plichta, Damian Rafal

AU - Løvendahl, Peter

AU - Lassen, Jan

AU - Noel, Samantha Joan

AU - Højberg, Ole

AU - Wright, André-Denis G

AU - Zhu, Zhigang

AU - Kristensen, Lise

AU - Nielsen, Henrik Bjørn

AU - Guldbrandtsen, Bernt

AU - Sahana, Goutam

PY - 2018/10/12

Y1 - 2018/10/12

N2 - Cattle and other ruminants produce large quantities of methane (~110 million metric tonnes per annum), which is a potent greenhouse gas affecting global climate change. Methane (CH4) is a natural by-product of gastro-enteric microbial fermentation of feedstuffs in the rumen and contributes to 6% of total CH4 emissions from anthropogenic-related sources. The extent to which the host genome and rumen microbiome influence CH4 emission is not yet well known. This study confirms individual variation in CH4 production was influenced by individual host (cow) genotype, as well as the host's rumen microbiome composition. Abundance of a small proportion of bacteria and archaea taxa were influenced to a limited extent by the host's genotype and certain taxa were associated with CH4 emissions. However, the cumulative effect of all bacteria and archaea on CH4 production was 13%, the host genetics (heritability) was 21% and the two are largely independent. This study demonstrates variation in CH4 emission is likely not modulated through cow genetic effects on the rumen microbiome. Therefore, the rumen microbiome and cow genome could be targeted independently, by breeding low methane-emitting cows and in parallel, by investigating possible strategies that target changes in the rumen microbiome to reduce CH4 emissions in the cattle industry.

AB - Cattle and other ruminants produce large quantities of methane (~110 million metric tonnes per annum), which is a potent greenhouse gas affecting global climate change. Methane (CH4) is a natural by-product of gastro-enteric microbial fermentation of feedstuffs in the rumen and contributes to 6% of total CH4 emissions from anthropogenic-related sources. The extent to which the host genome and rumen microbiome influence CH4 emission is not yet well known. This study confirms individual variation in CH4 production was influenced by individual host (cow) genotype, as well as the host's rumen microbiome composition. Abundance of a small proportion of bacteria and archaea taxa were influenced to a limited extent by the host's genotype and certain taxa were associated with CH4 emissions. However, the cumulative effect of all bacteria and archaea on CH4 production was 13%, the host genetics (heritability) was 21% and the two are largely independent. This study demonstrates variation in CH4 emission is likely not modulated through cow genetic effects on the rumen microbiome. Therefore, the rumen microbiome and cow genome could be targeted independently, by breeding low methane-emitting cows and in parallel, by investigating possible strategies that target changes in the rumen microbiome to reduce CH4 emissions in the cattle industry.

U2 - 10.1371/journal.pgen.1007580

DO - 10.1371/journal.pgen.1007580

M3 - Journal article

VL - 14

SP - e1007580

JO - P L o S Genetics

JF - P L o S Genetics

SN - 1553-7390

IS - 10

ER -