Home-based ‘exergaming’ was safe and significantly improved 6-min walking distance in patients with prostate cancer: a single-blinded randomised controlled trial

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OBJECTIVES: To explore the effects of 12 weeks of unsupervised home-based exergaming (i.e. technology-driven exercise) compared to usual care on physical function, body composition, quality of life (QoL) and fatigue in prostate cancer patients (PCa) on androgen deprivation therapy (ADT).

PATIENTS AND METHODS: In an assessor-blinded randomized controlled trial, 46 PCa patients (+65 years of age) with locally advanced or advanced stage disease undergoing ADT were randomized to 12 weeks of unsupervised home-based exergaming, or usual care from two hospitals in Denmark. The primary outcome of the study was 6-minute walking test (6MWT). Secondary outcomes were leg extensor power (LEP), body composition (lean- and fat- mass), self-reported physical functioning and global health status (EORTC QLQ-C30), QoL (FACT-P) and fatigue (FACT-F).

RESULTS: Significant improvement was seen in the exergaming group compared to the usual care group in the primary outcome 6MWT (mean difference: 21.5 meters; 95% confidence interval (CI) 3.2 - 39.9; p=0.023). No between group differences were seen for LEP (p= 0.227), lean body mass (p=0.100), fat body mass (p=0.092), self-reported physical functioning (p=0.084) and global health status (p=0.113), QoL (p=0.614) and fatigue (p=0.147).

CONCLUSION: 12 weeks of unsupervised home-based exergaming had an effect on the primary outcome 6MWT in PCa patients receiving ADT. However, no significant effects were found in secondary outcomes. The exergaming intervention appeared safe and could be an alternative to traditional aerobic and resistance training in this patient group.

TidsskriftBJU International
Sider (fra-til)600-608
Antal sider9
StatusUdgivet - okt. 2019

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