TY - JOUR
T1 - Home environment of 11-year-old children born to parents with schizophrenia or bipolar disorder - A controlled, 4-year follow-up study
T2 - The Danish High Risk and Resilience Study - VIA 11
AU - Krantz, Mette Falkenberg
AU - Hjorthøj, Carsten
AU - Brandt, Julie Marie
AU - Prøsch, Åsa Kremer
AU - Rohd, Sinnika Birkehøj
AU - Wilms, Martin
AU - Veddum, Lotte
AU - Steffensen, Nanna Lawaetz
AU - Knudsen, Christina Bruun
AU - Andreasen, Anna Krogh
AU - Stadsgaard, Henriette
AU - Hemager, Nicoline
AU - Burton, Birgitte Klee
AU - Gregersen, Maja
AU - Søndergaard, Anne
AU - Greve, Aja
AU - Gantriis, Ditte Lou
AU - Melau, Marianne
AU - Ohland, Jessica
AU - Mortensen, Preben Bo
AU - Bliksted, Vibeke
AU - Mors, Ole
AU - Thorup, Anne A.E.
AU - Nordentoft, Merete
N1 - Funding Information:
We thank the children and parents who participated in the study for their great contribution. We also thank Marianne Giørtz Pedersen and Carsten Bøcker Pedersen for their great contribution on the extraction of data from registers, and Benthe Emke Vink and Gøcke Mine Akkas for their great contribution with the data handling. This study was supported by The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), the Mental Health Services at the Capital Region of Denmark, Copenhagen University, Aarhus University, The Beatrice Surovell Haskell Fund and the Tryg Foundation. The funding sources had no influence on the study design or the reporting of data. All authors had full access to all the data in the study and accept responsibility for publication.
Funding Information:
The Danish High Risk and Resilience Study has received economic support from The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH, grant number R102-A9118 and R155-2014-1724), the Mental Health Services of the Capital Region of Denmark, University of Aarhus, University of Copenhagen, The Tryg Foundation, and The Beatrice Surovell Haskell Fund for Child Mental Health Research of Copenhagen. The funding sources have not had any influence on the study design or the reporting of data.
Publisher Copyright:
Copyright © The Author(s), 2021. Published by Cambridge University Press.
PY - 2023/4
Y1 - 2023/4
N2 - Background The home environment has a major impact on child development. Parental severe mental illness can pose a challenge to the home environment of a child. We aimed to examine the home environment of children of parents with schizophrenia or bipolar disorder and controls longitudinally through at-home assessments. Methods Assessments were conducted within The Danish High Risk and Resilience Study, a nationwide multi-center cohort study of children of parents with schizophrenia or bipolar disorder and population-based controls. The level of at-home stimulation and support was measured at age 7 (N = 508 children) and age 11 (N = 430 children) with the semi-structured HOME Inventory. Results from the 11-year follow-up study were analyzed and compared with 7-year baseline results to examine change across groups. Results At age 11, children of parents with schizophrenia and bipolar disorder had lower levels of stimulation and support than controls (mean (s.d.) = 46.16 (5.56), 46.87 (5.34) and 49.25 (4.37) respectively, p < 0.001). A higher proportion of children with parental schizophrenia or bipolar disorder lived in inadequate home environments at age 11, compared with controls (N (%) = 24 (15.0), 12 (12.2) and 6 (3.5) respectively, p < 0.003). The changes in home environment scores did not differ across groups from age 7 to age 11. Conclusions Assessed longitudinally from the children's age of 7 to 11, children of parents with schizophrenia or bipolar disorder had lower levels of stimulation and support in their homes than controls. Integrated support which can target practical, economic, social and health issues to improve the home environment is indicated.
AB - Background The home environment has a major impact on child development. Parental severe mental illness can pose a challenge to the home environment of a child. We aimed to examine the home environment of children of parents with schizophrenia or bipolar disorder and controls longitudinally through at-home assessments. Methods Assessments were conducted within The Danish High Risk and Resilience Study, a nationwide multi-center cohort study of children of parents with schizophrenia or bipolar disorder and population-based controls. The level of at-home stimulation and support was measured at age 7 (N = 508 children) and age 11 (N = 430 children) with the semi-structured HOME Inventory. Results from the 11-year follow-up study were analyzed and compared with 7-year baseline results to examine change across groups. Results At age 11, children of parents with schizophrenia and bipolar disorder had lower levels of stimulation and support than controls (mean (s.d.) = 46.16 (5.56), 46.87 (5.34) and 49.25 (4.37) respectively, p < 0.001). A higher proportion of children with parental schizophrenia or bipolar disorder lived in inadequate home environments at age 11, compared with controls (N (%) = 24 (15.0), 12 (12.2) and 6 (3.5) respectively, p < 0.003). The changes in home environment scores did not differ across groups from age 7 to age 11. Conclusions Assessed longitudinally from the children's age of 7 to 11, children of parents with schizophrenia or bipolar disorder had lower levels of stimulation and support in their homes than controls. Integrated support which can target practical, economic, social and health issues to improve the home environment is indicated.
KW - bipolar
KW - Home environment
KW - offspring
KW - schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=85120785502&partnerID=8YFLogxK
U2 - 10.1017/S0033291721004487
DO - 10.1017/S0033291721004487
M3 - Journal article
C2 - 37310315
AN - SCOPUS:85120785502
SN - 0033-2917
VL - 53
SP - 2563
EP - 2573
JO - Psychological Medicine
JF - Psychological Medicine
IS - 6
ER -