HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain

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  • Clemens Furnes, Department of Molecular Biology, University of Bergen, Norge
  • Thomas Arnesen, Department of Molecular Biology, University of Bergen, Norge
  • Peter Askjaer, Department of Molecular Biology, University of Aarhus, Danmark
  • Jørgen Kjems
  • Anne Marie Szilvay, Department of Molecular Biology, University of Bergen, Norge
The HIV-1 Rev regulatory protein binds as an oligomeric complex to viral RNA mediating nuclear export of incompletely spliced and non-spliced viral mRNAs encoding the viral structural proteins. However, the biological significance of the obligatory complex formation of Rev upon the viral RNA is unclear.
OriginalsprogEngelsk
TidsskriftRetrovirology
Vol/bind2
Sider (fra-til)39
ISSN1742-4690
DOI
StatusUdgivet - 2005

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