High yield from repeated testing for tuberculosis among high-risk citizens in Denmark

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Standard

High yield from repeated testing for tuberculosis among high-risk citizens in Denmark. / Staerke, Nina Breinholt; Smidt-Hansen, Torben; Oldenborg, Leni; Jensen, Torben Tranborg; Weinreich, Ulla Møller; Shakar, Shakil; Wejse, Christian; Hilberg, Ole; Fløe, Andreas.

I: International Journal of Infectious Diseases, Bind 102, 01.2021, s. 352-356.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Staerke, NB, Smidt-Hansen, T, Oldenborg, L, Jensen, TT, Weinreich, UM, Shakar, S, Wejse, C, Hilberg, O & Fløe, A 2021, 'High yield from repeated testing for tuberculosis among high-risk citizens in Denmark', International Journal of Infectious Diseases, bind 102, s. 352-356. https://doi.org/10.1016/j.ijid.2020.10.076

APA

Staerke, N. B., Smidt-Hansen, T., Oldenborg, L., Jensen, T. T., Weinreich, U. M., Shakar, S., Wejse, C., Hilberg, O., & Fløe, A. (2021). High yield from repeated testing for tuberculosis among high-risk citizens in Denmark. International Journal of Infectious Diseases, 102, 352-356. https://doi.org/10.1016/j.ijid.2020.10.076

CBE

Staerke NB, Smidt-Hansen T, Oldenborg L, Jensen TT, Weinreich UM, Shakar S, Wejse C, Hilberg O, Fløe A. 2021. High yield from repeated testing for tuberculosis among high-risk citizens in Denmark. International Journal of Infectious Diseases. 102:352-356. https://doi.org/10.1016/j.ijid.2020.10.076

MLA

Vancouver

Staerke NB, Smidt-Hansen T, Oldenborg L, Jensen TT, Weinreich UM, Shakar S o.a. High yield from repeated testing for tuberculosis among high-risk citizens in Denmark. International Journal of Infectious Diseases. 2021 jan;102:352-356. https://doi.org/10.1016/j.ijid.2020.10.076

Author

Staerke, Nina Breinholt ; Smidt-Hansen, Torben ; Oldenborg, Leni ; Jensen, Torben Tranborg ; Weinreich, Ulla Møller ; Shakar, Shakil ; Wejse, Christian ; Hilberg, Ole ; Fløe, Andreas. / High yield from repeated testing for tuberculosis among high-risk citizens in Denmark. I: International Journal of Infectious Diseases. 2021 ; Bind 102. s. 352-356.

Bibtex

@article{6490675271e84102a8d06ecc6edf27b7,
title = "High yield from repeated testing for tuberculosis among high-risk citizens in Denmark",
abstract = "BACKGROUND: Screening for tuberculosis among socially marginalized citizens have been implemented in many urban areas in low-incidence countries including Denmark. This study aims to describe the findings of the screening programs for tuberculosis (TB) and latent tuberculosis (LTBI) used in the western part of Denmark in the period 2014-2019.METHODS: Data was collected retrospectively on test results from interferon-gamma release assays (IGRA), sputum samples and chest X-rays performed as part of organized TB and LTBI screening among 1024 socially marginalized citizens in urban areas of western Denmark in 2014-2019.RESULTS: The overall TB incidence was 2148/100.000 and number needed to screen to find one TB case was 39, while the incidence of LTBI in the group screened with IGRA was 17.500/100.000. Testing with spot sputum yielded a TB rate of 2.5% compared to 2.7% when IGRA was used and similar proportions of cases were smear-negative. In total, 38.9% of TB diagnoses were obtained from 2. or 3. round of repeated screening procedure.CONCLUSION: We demonstrated a strikingly high incidence of TB and LTBI among socially marginalized citizens in Denmark. Results from screening with spot sputum assays and IGRAs are comparable in diagnosing TB in this screening setting.",
author = "Staerke, {Nina Breinholt} and Torben Smidt-Hansen and Leni Oldenborg and Jensen, {Torben Tranborg} and Weinreich, {Ulla M{\o}ller} and Shakil Shakar and Christian Wejse and Ole Hilberg and Andreas Fl{\o}e",
note = "Copyright {\textcopyright} 2020. Published by Elsevier Ltd.",
year = "2021",
month = jan,
doi = "10.1016/j.ijid.2020.10.076",
language = "English",
volume = "102",
pages = "352--356",
journal = "International Journal of Infectious Diseases",
issn = "1201-9712",
publisher = "Elsevier Ltd",

}

RIS

TY - JOUR

T1 - High yield from repeated testing for tuberculosis among high-risk citizens in Denmark

AU - Staerke, Nina Breinholt

AU - Smidt-Hansen, Torben

AU - Oldenborg, Leni

AU - Jensen, Torben Tranborg

AU - Weinreich, Ulla Møller

AU - Shakar, Shakil

AU - Wejse, Christian

AU - Hilberg, Ole

AU - Fløe, Andreas

N1 - Copyright © 2020. Published by Elsevier Ltd.

PY - 2021/1

Y1 - 2021/1

N2 - BACKGROUND: Screening for tuberculosis among socially marginalized citizens have been implemented in many urban areas in low-incidence countries including Denmark. This study aims to describe the findings of the screening programs for tuberculosis (TB) and latent tuberculosis (LTBI) used in the western part of Denmark in the period 2014-2019.METHODS: Data was collected retrospectively on test results from interferon-gamma release assays (IGRA), sputum samples and chest X-rays performed as part of organized TB and LTBI screening among 1024 socially marginalized citizens in urban areas of western Denmark in 2014-2019.RESULTS: The overall TB incidence was 2148/100.000 and number needed to screen to find one TB case was 39, while the incidence of LTBI in the group screened with IGRA was 17.500/100.000. Testing with spot sputum yielded a TB rate of 2.5% compared to 2.7% when IGRA was used and similar proportions of cases were smear-negative. In total, 38.9% of TB diagnoses were obtained from 2. or 3. round of repeated screening procedure.CONCLUSION: We demonstrated a strikingly high incidence of TB and LTBI among socially marginalized citizens in Denmark. Results from screening with spot sputum assays and IGRAs are comparable in diagnosing TB in this screening setting.

AB - BACKGROUND: Screening for tuberculosis among socially marginalized citizens have been implemented in many urban areas in low-incidence countries including Denmark. This study aims to describe the findings of the screening programs for tuberculosis (TB) and latent tuberculosis (LTBI) used in the western part of Denmark in the period 2014-2019.METHODS: Data was collected retrospectively on test results from interferon-gamma release assays (IGRA), sputum samples and chest X-rays performed as part of organized TB and LTBI screening among 1024 socially marginalized citizens in urban areas of western Denmark in 2014-2019.RESULTS: The overall TB incidence was 2148/100.000 and number needed to screen to find one TB case was 39, while the incidence of LTBI in the group screened with IGRA was 17.500/100.000. Testing with spot sputum yielded a TB rate of 2.5% compared to 2.7% when IGRA was used and similar proportions of cases were smear-negative. In total, 38.9% of TB diagnoses were obtained from 2. or 3. round of repeated screening procedure.CONCLUSION: We demonstrated a strikingly high incidence of TB and LTBI among socially marginalized citizens in Denmark. Results from screening with spot sputum assays and IGRAs are comparable in diagnosing TB in this screening setting.

U2 - 10.1016/j.ijid.2020.10.076

DO - 10.1016/j.ijid.2020.10.076

M3 - Journal article

C2 - 33130208

VL - 102

SP - 352

EP - 356

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

SN - 1201-9712

ER -