-
Uddannelse
Find uddannelse
Studievejledning
Kvalitet
- Forskning
-
Samarbejde
Virksomheder
Kommuner og regioner
Gymnasier
Myndigheder
-
Om AU
Organisation
Kontakt
Om AU
- Organisation
- Ledelse
- Strategi
- AU i tal
- AU's historie
- Internationalt samarbejde
- Bæredygtighed
- Campus 2.0
- Diversitet og ligestilling
- Ledige stillinger
- Presse
- Kontakt
Heat stress delays detoxification of phenanthrene in the springtail Folsomia candida
Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review
Links
- https://www.sciencedirect.com/science/article/pii/S0045653522036128
Forlagets udgivne version
DOI
- https://doi.org/10.1016/j.chemosphere.2022.137119
Forlagets udgivne version
- Wencai Dai, Southwest University ,
- Martin Holmstrup
- Stine Slotsbo
- Ruben Bakker, Vrije Universiteit Amsterdam, Holland
- Christian Damgaard
- Cornelis A.M. van Gestel, Vrije Universiteit Amsterdam, Holland
Climate change has intensified the occurrence of heat waves, resulting in organisms being exposed to thermal and chemical stress at the same time. The effects of mild heat shock combined with sublethal concentrations of phenanthrene (PHE) on defense mechanisms in springtails Folsomia candida were investigated. The transcription of Heat Shock Protein 70 (HSP70) was significantly upregulated by heat shock but tended to reach the control levels after 42 h of recovery. The transcription of cytochrome P450 3A13 (CYP3A13) was upregulated 3–13 fold by PHE but suppressed by heat shock. The suppression by heat shock might contribute to the reduced detoxification of PHE during high-temperature exposure. In line with this, we found that the internal PHE concentration was approximately 70% higher in heat-shocked springtails than in animals kept at control temperature. In general, the transcription of genes encoding enzymes of detoxification phase Ⅱ (glutathione S-transferase 3) and phase Ⅲ (ABC transporter 1) and the activity of antioxidant defense enzymes (superoxide dismutase and catalase) were less influenced than genes encoding phase I detoxification mechanisms (CYP3A13). These results indicate that heat shock delays the detoxification of PHE in springtails.
| Originalsprog | Engelsk |
|---|---|
| Artikelnummer | 137119 |
| Tidsskrift | Chemosphere |
| Vol/bind | 311 |
| Nummer | Part 2 |
| ISSN | 0045-6535 |
| DOI | |
| Status | Udgivet - jan. 2023 |
Se relationer på Aarhus Universitet Citationsformater
ID: 301098623