Health-Related Quality of Life of People Living with COPD in a Semiurban Area of Western Nepal: A Community-Based Study

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  • Tara Ballav Adhikari
  • Anupa Rijal, Nepal Development Society, Chitwan, Nepal, Syddansk Universitet
  • ,
  • Pawan Acharya, Nepal Development Society, Chitwan, Nepal
  • ,
  • Marieann Högman, Uppsala University and Uppsala Clinical Research Center, Uppsala University, Sweden.
  • ,
  • Arjun Karki, HAMS Hospital
  • ,
  • Arne Drews, Nepalmed
  • ,
  • Brendan G Cooper, University Hospitals Birmingham, Birmingham, UK.
  • ,
  • Torben Sigsgaard
  • Dinesh Neupane, COBIN Project, Nepal Development Society, Bharatpur-10, Narayani Zone, Chitwan, Nepal., Nepal Development Society (NEDS), Chitwan, Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD, USA.
  • ,
  • Per Kallestrup

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality in Nepal. It is a progressive lung disease and has a significant impact on the quality of life of patients. Health-related quality of life (HRQOL) reflects the health- and disease-related facets of quality of life. Limited studies have assessed the impact of COPD on HRQOL and associated factors in Nepal. This study is based on a cross-sectional household survey data from a semiurban area of Western Nepal. A validated Nepali version of St George's Respiratory Questionnaire (SGRQ) was used to measure the HRQOL. COPD was defined together with post-bronchodilator airflow obstruction and the presence of respiratory symptoms. Post-bronchodilator airflow obstruction was defined as Forced Expiratory Volume in 1st second (FEV1) to Forced Vital Capacity (FVC) ratio < 0.70. COPD was diagnosed in 122 participants, and their median (IQR) total score of HRQOL was 40 (26 - 69); the score of symptoms, activity, and impact area were 53 (37 - 74), 57 (36 - 86), and 26 (13 - 62), respectively. The overall HRQOL was significantly different in terms of age, occupational status, physical activity, and comorbidities. Disease severity and the presence of respiratory symptoms had a significant difference in HRQOL (p = 0.0001). Appropriate measures to improve conditions and addressing the associated factors like respiratory symptoms and enhancing physical activity are necessary and important.

OriginalsprogEngelsk
TidsskriftC O P D
Sider (fra-til)1-14
Antal sider14
ISSN1541-2555
DOI
StatusE-pub ahead of print - 10 maj 2021

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