Gonadotropin-releasing hormone agonist ovulation trigger—beyond OHSS prevention

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In this review the advantages of the gonadotropin-releasing hormone agonist (GnRHa) trigger are discussed beyond those immediately associated with ovarian hyperstimulation syndrome (OHSS) prevention. The GnRHa trigger concept has sparked the development of novel protocols, enriching the assisted reproductive technology (ART) armamentarium for the benefit of present and future patients. Thus, GnRHa trigger already has a pivotal role, not only for the standard in vitro fertilisation (IVF) patient, but also for patient groups like oocyte donors, cancer patients, patients with poor ovarian reserve, and patients with immature oocyte syndrome and empty follicle syndrome. Herein, we discuss the importance of the GnRHa-elicited midcycle FSH surge and the potential improvement in oocyte yield and embryo competence.

OriginalsprogEngelsk
BogserieUpsala Journal of Medical Sciences
Vol/bind125
Nummer2
Sider (fra-til)138-143
Antal sider6
ISSN0300-9734
DOI
StatusUdgivet - maj 2020

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