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Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses

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Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses. / Kapun, Martin; Barrón, Maite G.; Staubach, Fabian; Obbard, Darren J.; Wiberg, R. Axel W.; Vieira, Jorge; Goubert, Clément; Rota-Stabelli, Omar; Kankare, Maaria; Bogaerts-Márquez, María; Haudry, Annabelle; Waidele, Lena; Kozeretska, Iryna; Pasyukova, Elena G.; Loeschcke, Volker; Pascual, Marta; Vieira, Cristina P.; Serga, Svitlana; Montchamp-Moreau, Catherine; Abbott, Jessica; Gibert, Patricia; Porcelli, Damiano; Posnien, Nico; Sánchez-Gracia, Alejandro; Grath, Sonja; Sucena, Élio; Bergland, Alan O.; Guerreiro, Maria Pilar Garcia; Onder, Banu Sebnem; Argyridou, Eliza; Guio, Lain; Schou, Mads Fristrup; Deplancke, Bart; Vieira, Cristina; Ritchie, Michael G.; Zwaan, Bas J.; Tauber, Eran; Orengo, Dorcas J.; Puerma, Eva; Aguadé, Montserrat; Schmidt, Paul; Parsch, John; Betancourt, Andrea J.; Flatt, Thomas; González, Josefa.

I: Molecular Biology and Evolution, Bind 37, Nr. 9, 09.2020, s. 2661-2678.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Kapun, M, Barrón, MG, Staubach, F, Obbard, DJ, Wiberg, RAW, Vieira, J, Goubert, C, Rota-Stabelli, O, Kankare, M, Bogaerts-Márquez, M, Haudry, A, Waidele, L, Kozeretska, I, Pasyukova, EG, Loeschcke, V, Pascual, M, Vieira, CP, Serga, S, Montchamp-Moreau, C, Abbott, J, Gibert, P, Porcelli, D, Posnien, N, Sánchez-Gracia, A, Grath, S, Sucena, É, Bergland, AO, Guerreiro, MPG, Onder, BS, Argyridou, E, Guio, L, Schou, MF, Deplancke, B, Vieira, C, Ritchie, MG, Zwaan, BJ, Tauber, E, Orengo, DJ, Puerma, E, Aguadé, M, Schmidt, P, Parsch, J, Betancourt, AJ, Flatt, T & González, J 2020, 'Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses', Molecular Biology and Evolution, bind 37, nr. 9, s. 2661-2678. https://doi.org/10.1093/molbev/msaa120

APA

Kapun, M., Barrón, M. G., Staubach, F., Obbard, D. J., Wiberg, R. A. W., Vieira, J., Goubert, C., Rota-Stabelli, O., Kankare, M., Bogaerts-Márquez, M., Haudry, A., Waidele, L., Kozeretska, I., Pasyukova, E. G., Loeschcke, V., Pascual, M., Vieira, C. P., Serga, S., Montchamp-Moreau, C., ... González, J. (2020). Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses. Molecular Biology and Evolution, 37(9), 2661-2678. https://doi.org/10.1093/molbev/msaa120

CBE

Kapun M, Barrón MG, Staubach F, Obbard DJ, Wiberg RAW, Vieira J, Goubert C, Rota-Stabelli O, Kankare M, Bogaerts-Márquez M, Haudry A, Waidele L, Kozeretska I, Pasyukova EG, Loeschcke V, Pascual M, Vieira CP, Serga S, Montchamp-Moreau C, Abbott J, Gibert P, Porcelli D, Posnien N, Sánchez-Gracia A, Grath S, Sucena É, Bergland AO, Guerreiro MPG, Onder BS, Argyridou E, Guio L, Schou MF, Deplancke B, Vieira C, Ritchie MG, Zwaan BJ, Tauber E, Orengo DJ, Puerma E, Aguadé M, Schmidt P, Parsch J, Betancourt AJ, Flatt T, González J. 2020. Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses. Molecular Biology and Evolution. 37(9):2661-2678. https://doi.org/10.1093/molbev/msaa120

MLA

Vancouver

Kapun M, Barrón MG, Staubach F, Obbard DJ, Wiberg RAW, Vieira J o.a. Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses. Molecular Biology and Evolution. 2020 sep;37(9):2661-2678. https://doi.org/10.1093/molbev/msaa120

Author

Kapun, Martin ; Barrón, Maite G. ; Staubach, Fabian ; Obbard, Darren J. ; Wiberg, R. Axel W. ; Vieira, Jorge ; Goubert, Clément ; Rota-Stabelli, Omar ; Kankare, Maaria ; Bogaerts-Márquez, María ; Haudry, Annabelle ; Waidele, Lena ; Kozeretska, Iryna ; Pasyukova, Elena G. ; Loeschcke, Volker ; Pascual, Marta ; Vieira, Cristina P. ; Serga, Svitlana ; Montchamp-Moreau, Catherine ; Abbott, Jessica ; Gibert, Patricia ; Porcelli, Damiano ; Posnien, Nico ; Sánchez-Gracia, Alejandro ; Grath, Sonja ; Sucena, Élio ; Bergland, Alan O. ; Guerreiro, Maria Pilar Garcia ; Onder, Banu Sebnem ; Argyridou, Eliza ; Guio, Lain ; Schou, Mads Fristrup ; Deplancke, Bart ; Vieira, Cristina ; Ritchie, Michael G. ; Zwaan, Bas J. ; Tauber, Eran ; Orengo, Dorcas J. ; Puerma, Eva ; Aguadé, Montserrat ; Schmidt, Paul ; Parsch, John ; Betancourt, Andrea J. ; Flatt, Thomas ; González, Josefa. / Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses. I: Molecular Biology and Evolution. 2020 ; Bind 37, Nr. 9. s. 2661-2678.

Bibtex

@article{72194a32a867411cbdcc84be4182fdee,
title = "Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses",
abstract = "Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterize variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples.",
keywords = "adaptation, demography, clines, population genomics, selection, SNPs, structural variants",
author = "Martin Kapun and Barr{\'o}n, {Maite G.} and Fabian Staubach and Obbard, {Darren J.} and Wiberg, {R. Axel W.} and Jorge Vieira and Cl{\'e}ment Goubert and Omar Rota-Stabelli and Maaria Kankare and Mar{\'i}a Bogaerts-M{\'a}rquez and Annabelle Haudry and Lena Waidele and Iryna Kozeretska and Pasyukova, {Elena G.} and Volker Loeschcke and Marta Pascual and Vieira, {Cristina P.} and Svitlana Serga and Catherine Montchamp-Moreau and Jessica Abbott and Patricia Gibert and Damiano Porcelli and Nico Posnien and Alejandro S{\'a}nchez-Gracia and Sonja Grath and {\'E}lio Sucena and Bergland, {Alan O.} and Guerreiro, {Maria Pilar Garcia} and Onder, {Banu Sebnem} and Eliza Argyridou and Lain Guio and Schou, {Mads Fristrup} and Bart Deplancke and Cristina Vieira and Ritchie, {Michael G.} and Zwaan, {Bas J.} and Eran Tauber and Orengo, {Dorcas J.} and Eva Puerma and Montserrat Aguad{\'e} and Paul Schmidt and John Parsch and Betancourt, {Andrea J.} and Thomas Flatt and Josefa Gonz{\'a}lez",
year = "2020",
month = sep,
doi = "10.1093/molbev/msaa120",
language = "English",
volume = "37",
pages = "2661--2678",
journal = "Molecular Biology and Evolution",
issn = "0737-4038",
publisher = "Oxford University Press",
number = "9",

}

RIS

TY - JOUR

T1 - Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses

AU - Kapun, Martin

AU - Barrón, Maite G.

AU - Staubach, Fabian

AU - Obbard, Darren J.

AU - Wiberg, R. Axel W.

AU - Vieira, Jorge

AU - Goubert, Clément

AU - Rota-Stabelli, Omar

AU - Kankare, Maaria

AU - Bogaerts-Márquez, María

AU - Haudry, Annabelle

AU - Waidele, Lena

AU - Kozeretska, Iryna

AU - Pasyukova, Elena G.

AU - Loeschcke, Volker

AU - Pascual, Marta

AU - Vieira, Cristina P.

AU - Serga, Svitlana

AU - Montchamp-Moreau, Catherine

AU - Abbott, Jessica

AU - Gibert, Patricia

AU - Porcelli, Damiano

AU - Posnien, Nico

AU - Sánchez-Gracia, Alejandro

AU - Grath, Sonja

AU - Sucena, Élio

AU - Bergland, Alan O.

AU - Guerreiro, Maria Pilar Garcia

AU - Onder, Banu Sebnem

AU - Argyridou, Eliza

AU - Guio, Lain

AU - Schou, Mads Fristrup

AU - Deplancke, Bart

AU - Vieira, Cristina

AU - Ritchie, Michael G.

AU - Zwaan, Bas J.

AU - Tauber, Eran

AU - Orengo, Dorcas J.

AU - Puerma, Eva

AU - Aguadé, Montserrat

AU - Schmidt, Paul

AU - Parsch, John

AU - Betancourt, Andrea J.

AU - Flatt, Thomas

AU - González, Josefa

PY - 2020/9

Y1 - 2020/9

N2 - Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterize variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples.

AB - Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterize variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples.

KW - adaptation, demography

KW - clines

KW - population genomics

KW - selection

KW - SNPs

KW - structural variants

UR - http://www.scopus.com/inward/record.url?scp=85090025034&partnerID=8YFLogxK

U2 - 10.1093/molbev/msaa120

DO - 10.1093/molbev/msaa120

M3 - Journal article

C2 - 32413142

AN - SCOPUS:85090025034

VL - 37

SP - 2661

EP - 2678

JO - Molecular Biology and Evolution

JF - Molecular Biology and Evolution

SN - 0737-4038

IS - 9

ER -