GeneRecon—A coalescent based tool for fine-scale association mapping

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  • Center for Bioinformatik (BiRC)
  • Datalogisk Institut
  • Genetik og Økologi, Biologisk Institut
  • Molekylærbiologisk Institut
GeneRecon is a tool for fine-scale association mapping using a coalescence model. GeneRecon takes as input case-control data from phased or unphased SNP and micro-satellite genotypes. The posterior distribution of disease locus position is obtained by Metropolis Hastings sampling in the state space of genealogies. Input format, search strategy, and the sampled statistics can be configured through the Guile Scheme programming language embedded in GeneRecon, making GeneRecon highly configurable.
OriginalsprogEngelsk
TidsskriftBioinformatics
Vol/bind22
Nummer18
Sider (fra-til)2317–2318
Antal sider2
ISSN1367-4803
StatusUdgivet - 2006

Bibliografisk note

Paper id:: doi:10.1093/bioinformatics/btl153

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