-
Uddannelse
Find uddannelse
Studievejledning
Kvalitet
- Forskning
-
Samarbejde
Virksomheder
Kommuner og regioner
Gymnasier
Myndigheder
-
Om AU
Organisation
Kontakt
Om AU
- Organisation
- Ledelse
- Strategi
- AU i tal
- AU's historie
- Internationalt samarbejde
- Bæredygtighed
- Campus 2.0
- Diversitet og ligestilling
- Ledige stillinger
- Presse
- Kontakt
Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines
Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review
- Martin Bøgsted
- Johanne Marie Holst
- Kirsten Fogd, Danmark
- Steffen Falgreen Larsen ,
- Suzette Sørensen, Danmark
- Alexander Schmitz
- Anne Bukh, Danmark
- Hans Erik Johnsen, Danmark
- Mette Nyegaard, Danmark
- Karen Dybkær, Danmark
- Hæmatologisk Afdeling, Aalborg Sygehus
- Institut for Klinisk Medicin - Hæmatologisk Afdeling, Aalborg Sygehus
Recent reports indicate that in vitro drug screens combined with gene expression profiles (GEP) of cancer cell lines may generate informative signatures predicting the clinical outcome of chemotherapy. In multiple myeloma (MM) a range of new drugs have been introduced and now challenge conventional therapy including high dose melphalan. Consequently, the generation of predictive signatures for response to melphalan may have a clinical impact. The hypothesis is that melphalan screens and GEPs of B-cell cancer cell lines combined with multivariate statistics may provide predictive clinical information.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | P L o S One |
| Vol/bind | 6 |
| Nummer | 4 |
| Sider (fra-til) | e19322 |
| Antal sider | 9 |
| ISSN | 1932-6203 |
| DOI | |
| Status | Udgivet - 1 jan. 2011 |
Se relationer på Aarhus Universitet Citationsformater
ID: 39867664