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Fetal programming and Wilms tumor

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Fetal programming and Wilms tumor. / Heck, Julia E; He, Di; Janzen, Carla; Federman, Noah; Olsen, Jorn; Ritz, Beate; Hansen, Johnni.

I: Pediatric Blood & Cancer, Bind 66, Nr. 1, e27461, 01.2019.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Heck, JE, He, D, Janzen, C, Federman, N, Olsen, J, Ritz, B & Hansen, J 2019, 'Fetal programming and Wilms tumor', Pediatric Blood & Cancer, bind 66, nr. 1, e27461. https://doi.org/10.1002/pbc.27461

APA

Heck, J. E., He, D., Janzen, C., Federman, N., Olsen, J., Ritz, B., & Hansen, J. (2019). Fetal programming and Wilms tumor. Pediatric Blood & Cancer, 66(1), [e27461]. https://doi.org/10.1002/pbc.27461

CBE

Heck JE, He D, Janzen C, Federman N, Olsen J, Ritz B, Hansen J. 2019. Fetal programming and Wilms tumor. Pediatric Blood & Cancer. 66(1). https://doi.org/10.1002/pbc.27461

MLA

Heck, Julia E o.a.. "Fetal programming and Wilms tumor". Pediatric Blood & Cancer. 2019. 66(1). https://doi.org/10.1002/pbc.27461

Vancouver

Heck JE, He D, Janzen C, Federman N, Olsen J, Ritz B o.a. Fetal programming and Wilms tumor. Pediatric Blood & Cancer. 2019 jan;66(1). e27461. https://doi.org/10.1002/pbc.27461

Author

Heck, Julia E ; He, Di ; Janzen, Carla ; Federman, Noah ; Olsen, Jorn ; Ritz, Beate ; Hansen, Johnni. / Fetal programming and Wilms tumor. I: Pediatric Blood & Cancer. 2019 ; Bind 66, Nr. 1.

Bibtex

@article{b78dd96abf4f4abdb8a37caee29c377d,
title = "Fetal programming and Wilms tumor",
abstract = "Background The {"}fetal programming{"} hypothesis has been evaluated in many adult diseases including cancer, but not for Wilms tumor. Wilms tumor has been related to high birthweight, but little is known about other growth metrics such as a baby's birth length, ponderal index, or placenta size, which can shed additional light on growth patterns. Methods Results Cases of Wilms tumor (N = 217) were taken from the Danish Cancer Registry, and controls (N = 4340) were randomly selected from the Population Register and matched to cases by sex and age. Linkage to the Medical Births Registry provided information on gestational factors and fetal growth measurements, while linkage to the Patient Register provided information on maternal and child health conditions. Despite having typically normal to higher birthweights, Wilms tumor cases had smaller placentas (4000 g; OR = 1.57; 95{\%} CI, 1.11-2.22), birth length 55 cm or longer (OR = 1.74; 95{\%} CI, 1.09-2.78), and being large for gestational age (OR = 1.79; 95{\%} CI, 1.08-2.96). Conclusions Our study corroborates earlier studies showing associations with high birthweight and suggests associations between Wilms tumor and decreased placental size and low placenta-to-birthweight ratio.",
keywords = "birthweight, body size, fetal development, nephroblastoma, placenta",
author = "Heck, {Julia E} and Di He and Carla Janzen and Noah Federman and Jorn Olsen and Beate Ritz and Johnni Hansen",
note = "{\circledC} 2018 Wiley Periodicals, Inc.",
year = "2019",
month = "1",
doi = "10.1002/pbc.27461",
language = "English",
volume = "66",
journal = "Pediatric Blood & Cancer",
issn = "1545-5009",
publisher = "JohnWiley & Sons, Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Fetal programming and Wilms tumor

AU - Heck, Julia E

AU - He, Di

AU - Janzen, Carla

AU - Federman, Noah

AU - Olsen, Jorn

AU - Ritz, Beate

AU - Hansen, Johnni

N1 - © 2018 Wiley Periodicals, Inc.

PY - 2019/1

Y1 - 2019/1

N2 - Background The "fetal programming" hypothesis has been evaluated in many adult diseases including cancer, but not for Wilms tumor. Wilms tumor has been related to high birthweight, but little is known about other growth metrics such as a baby's birth length, ponderal index, or placenta size, which can shed additional light on growth patterns. Methods Results Cases of Wilms tumor (N = 217) were taken from the Danish Cancer Registry, and controls (N = 4340) were randomly selected from the Population Register and matched to cases by sex and age. Linkage to the Medical Births Registry provided information on gestational factors and fetal growth measurements, while linkage to the Patient Register provided information on maternal and child health conditions. Despite having typically normal to higher birthweights, Wilms tumor cases had smaller placentas (4000 g; OR = 1.57; 95% CI, 1.11-2.22), birth length 55 cm or longer (OR = 1.74; 95% CI, 1.09-2.78), and being large for gestational age (OR = 1.79; 95% CI, 1.08-2.96). Conclusions Our study corroborates earlier studies showing associations with high birthweight and suggests associations between Wilms tumor and decreased placental size and low placenta-to-birthweight ratio.

AB - Background The "fetal programming" hypothesis has been evaluated in many adult diseases including cancer, but not for Wilms tumor. Wilms tumor has been related to high birthweight, but little is known about other growth metrics such as a baby's birth length, ponderal index, or placenta size, which can shed additional light on growth patterns. Methods Results Cases of Wilms tumor (N = 217) were taken from the Danish Cancer Registry, and controls (N = 4340) were randomly selected from the Population Register and matched to cases by sex and age. Linkage to the Medical Births Registry provided information on gestational factors and fetal growth measurements, while linkage to the Patient Register provided information on maternal and child health conditions. Despite having typically normal to higher birthweights, Wilms tumor cases had smaller placentas (4000 g; OR = 1.57; 95% CI, 1.11-2.22), birth length 55 cm or longer (OR = 1.74; 95% CI, 1.09-2.78), and being large for gestational age (OR = 1.79; 95% CI, 1.08-2.96). Conclusions Our study corroborates earlier studies showing associations with high birthweight and suggests associations between Wilms tumor and decreased placental size and low placenta-to-birthweight ratio.

KW - birthweight

KW - body size

KW - fetal development

KW - nephroblastoma

KW - placenta

U2 - 10.1002/pbc.27461

DO - 10.1002/pbc.27461

M3 - Journal article

VL - 66

JO - Pediatric Blood & Cancer

JF - Pediatric Blood & Cancer

SN - 1545-5009

IS - 1

M1 - e27461

ER -