TY - JOUR
T1 - Expanded utility of the R package, qgg, with applications within genomic medicine
AU - Rohde, Palle Duun
AU - Fourie Sørensen, Izel
AU - Sørensen, Peter
N1 - Publisher Copyright:
© The Author(s) 2023. Published by Oxford University Press.
PY - 2023/11
Y1 - 2023/11
N2 - Here, we present an expanded utility of the R package qgg for genetic analyses of complex traits and diseases. One of the major updates of the package is, that it now includes Bayesian linear regression modeling procedures, which provide a unified framework for mapping of genetic variants, estimation of heritability and genomic prediction from either individual level data or from genome-wide association study summary data. With this release, the qgg package now provides a wealth of the commonly used methods in analysis of complex traits and diseases, without the need to switch between software and data formats.
AB - Here, we present an expanded utility of the R package qgg for genetic analyses of complex traits and diseases. One of the major updates of the package is, that it now includes Bayesian linear regression modeling procedures, which provide a unified framework for mapping of genetic variants, estimation of heritability and genomic prediction from either individual level data or from genome-wide association study summary data. With this release, the qgg package now provides a wealth of the commonly used methods in analysis of complex traits and diseases, without the need to switch between software and data formats.
UR - http://www.scopus.com/inward/record.url?scp=85176506046&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/btad656
DO - 10.1093/bioinformatics/btad656
M3 - Journal article
C2 - 37882742
AN - SCOPUS:85176506046
SN - 1367-4803
VL - 39
JO - Bioinformatics (Oxford, England)
JF - Bioinformatics (Oxford, England)
IS - 11
M1 - btad656
ER -