TY - JOUR
T1 - Enzyme immobilization in hydrogels
T2 - A perfect liaison for efficient and sustainable biocatalysis
AU - Meyer, Johanna
AU - Meyer, Lars-Erik
AU - Kara, Selin
PY - 2022/3
Y1 - 2022/3
N2 - Biocatalysis is an established chemical synthesis technology that has by no means been restricted to research laboratories. The use of enzymes for organic synthesis has evolved greatly from early development to proof-of-concept – from small batch production to industrial scale. Different enzyme immobilization strategies contributed to this success story. Recently, the use of hydrogel materials for the immobilization of enzymes has been attracting great interest. Within this review, we pay special attention to recent developments in this key emerging field of research. Firstly, we will briefly introduce the concepts of both biocatalysis and hydrogel worlds. Then, we list recent interesting publications that link both concepts. Finally, we provide an outlook and comment on future perspectives of further exploration of enzyme immobilization strategies in hydrogels.
AB - Biocatalysis is an established chemical synthesis technology that has by no means been restricted to research laboratories. The use of enzymes for organic synthesis has evolved greatly from early development to proof-of-concept – from small batch production to industrial scale. Different enzyme immobilization strategies contributed to this success story. Recently, the use of hydrogel materials for the immobilization of enzymes has been attracting great interest. Within this review, we pay special attention to recent developments in this key emerging field of research. Firstly, we will briefly introduce the concepts of both biocatalysis and hydrogel worlds. Then, we list recent interesting publications that link both concepts. Finally, we provide an outlook and comment on future perspectives of further exploration of enzyme immobilization strategies in hydrogels.
KW - biocatalysis
KW - enzyme immobilization
KW - hydrogels
KW - process intensification
KW - sustainable synthesis
UR - http://www.scopus.com/inward/record.url?scp=85121480447&partnerID=8YFLogxK
U2 - 10.1002/elsc.202100087
DO - 10.1002/elsc.202100087
M3 - Review
C2 - 35382546
SN - 1618-0240
VL - 22
SP - 165
EP - 177
JO - Engineering in Life Sciences
JF - Engineering in Life Sciences
IS - 3-4
ER -