Discovery pipeline for epigenetically deregulated miRNAs in cancer: integration of primary miRNA transcription

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  • Toby Hulf, Epigenetics Laboratory, Cancer Research Program, Garvan Institute of Medical Research, Australien
  • Tennille Sibbritt, Epigenetics Laboratory, Cancer Research Program, Garvan Institute of Medical Research, Australien
  • Erik D Wiklund, Danmark
  • Saul Bert, Epigenetics Laboratory, Cancer Research Program, Garvan Institute of Medical Research, Australien
  • Dario Strbenac, Epigenetics Laboratory, Cancer Research Program, Garvan Institute of Medical Research, Australien
  • Aaron L Statham, Epigenetics Laboratory, Cancer Research Program, Garvan Institute of Medical Research, Australien
  • Mark D Robinson, Bioinformatics Division, Walter and Eliza Hall of Medical Research, Australien
  • Susan J Clark, St Vincent's Clinical School, University of NSW, St Vincent's Hospital, Australien
  • Molekylærbiologisk Institut
Cancer is commonly associated with widespread disruption of DNA methylation, chromatin modification and miRNA expression. In this study, we established a robust discovery pipeline to identify epigenetically deregulated miRNAs in cancer.
OriginalsprogEngelsk
TidsskriftB M C Genomics
Vol/bind12
Sider (fra-til)54
ISSN1471-2164
DOI
StatusUdgivet - 21 jan. 2011

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