TY - JOUR
T1 - Differential effects of 3-nitrooxypropanol supplementation on milk fatty acid profiles in 3 different dairy breeds
AU - Sirinayake Lokuge, Gayani Madushani
AU - Nielsen, Nicolaj I.
AU - Maigaard, Morten
AU - Lund, Peter
AU - Larsen, Lotte Bach
AU - Wiking, Lars
AU - Poulsen, Nina Aagaard
PY - 2025/3
Y1 - 2025/3
N2 - 3-Nitrooxypropanol (3-NOP) is a promising and approved antimethanogenic feed additive in dairy farming. The objective of this study was to evaluate breed-specific variation in milk fatty acids (FA) following 3-NOP supplementation. Milk FA composition was analyzed from 3 studies using Danish Holstein (DH), Danish Jersey (DJ), and Danish Red (DR) dairy cows respectively, fed control or 3-NOP supplemented diets. The 3-NOP was supplemented at a dose of 60 mg/kg feed DM. Bulk milk samples were analyzed for milk FA by GC flame ionization detection. The 3-NOP supplemented diets increased the proportion of short-chain fatty acids (SCFA) and decreased the proportion of C16:0 in the milk of DH cows. A similar tendency in milk FA composition induced by 3-NOP was observed in DJ cows; however, the extent of these changes was less pronounced, and no changes were observed in milk FA from DR cows. Indirect comparison among the breeds showed a higher proportion of SCFA in milk from DJ cows, a higher proportion of medium-chain FA in DR cows and a higher proportion of long-chain FA in DH cows. The effect of 3-NOP on milk FA composition appears to vary between breeds; however, this variation may also be influenced by differences in feeding regimens between breeds, making further studies worthwhile to better understand these interactions.
AB - 3-Nitrooxypropanol (3-NOP) is a promising and approved antimethanogenic feed additive in dairy farming. The objective of this study was to evaluate breed-specific variation in milk fatty acids (FA) following 3-NOP supplementation. Milk FA composition was analyzed from 3 studies using Danish Holstein (DH), Danish Jersey (DJ), and Danish Red (DR) dairy cows respectively, fed control or 3-NOP supplemented diets. The 3-NOP was supplemented at a dose of 60 mg/kg feed DM. Bulk milk samples were analyzed for milk FA by GC flame ionization detection. The 3-NOP supplemented diets increased the proportion of short-chain fatty acids (SCFA) and decreased the proportion of C16:0 in the milk of DH cows. A similar tendency in milk FA composition induced by 3-NOP was observed in DJ cows; however, the extent of these changes was less pronounced, and no changes were observed in milk FA from DR cows. Indirect comparison among the breeds showed a higher proportion of SCFA in milk from DJ cows, a higher proportion of medium-chain FA in DR cows and a higher proportion of long-chain FA in DH cows. The effect of 3-NOP on milk FA composition appears to vary between breeds; however, this variation may also be influenced by differences in feeding regimens between breeds, making further studies worthwhile to better understand these interactions.
UR - http://www.scopus.com/inward/record.url?scp=85219058141&partnerID=8YFLogxK
U2 - 10.3168/jdsc.2024-0656
DO - 10.3168/jdsc.2024-0656
M3 - Journal article
SN - 2666-9102
VL - 6
SP - 261
EP - 266
JO - JDS Communications
JF - JDS Communications
IS - 2
M1 - 6
ER -