Dialing in the Ratio of Covalent and Coordination Cross-links in Self-healing Hydrogels

Bidragets oversatte titel: Indkodning af Forholdet mellem Kovalente- og Koordinations-krydsbindinger i Selvhelende Hydrogeler

Amanda Andersen, Marie Krogsgaard, Henrik Birkedal

Publikation: KonferencebidragPosterForskning


Supported by the diverse chemistry of the catechol group, pH-responsive, mussel-inspired hydrogels has drawn considerable attention due to the presence of reversible catecholato–metal bonds, which incorporates self-healing properties. Through oxidation, catechols also participates in covalent cross-linking and as these impacts the abovementioned properties, it is of great interest to control the degree of which these are present; i.e. controlling the degree of catechol oxidation.
Until now, the catechols participating in the two cross-linking types have been the same. This way the actual ratio between the two types cannot be either predefined or controlled, as it is determined by the oxidation rate within the hydrogel.
Here, we report hydrogels in which the catechols participating in reversible (oxidation resistant catechol) and irreversible (classical catechol) cross-links are separated, enabling one to predefine the ratio of the two by altering the composition.
Bidragets oversatte titelIndkodning af Forholdet mellem Kovalente- og Koordinations-krydsbindinger i Selvhelende Hydrogeler
Publikationsdato4 jun. 2016
Antal sider1
StatusUdgivet - 4 jun. 2016
BegivenhedGordon Research Conference: Bioinspired Materials - Le Diablerets, Schweiz
Varighed: 6 jun. 201610 jun. 2016


KonferenceGordon Research Conference
ByLe Diablerets