Diagnostic accuracy of ultrasound-guided core biopsy of peripheral nerve sheath tumors

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Diagnostic accuracy of ultrasound-guided core biopsy of peripheral nerve sheath tumors. / Tottrup, Mikkel; Eriksen, Jacob D.; Hellfritzsch, Michel B. et al.

I: Journal of Clinical Ultrasound, Bind 48, Nr. 3, 2020, s. 134-138.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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Tottrup, Mikkel ; Eriksen, Jacob D. ; Hellfritzsch, Michel B. et al. / Diagnostic accuracy of ultrasound-guided core biopsy of peripheral nerve sheath tumors. I: Journal of Clinical Ultrasound. 2020 ; Bind 48, Nr. 3. s. 134-138.

Bibtex

@article{1dad6ce4f73e46c6877ee93fab1534a7,
title = "Diagnostic accuracy of ultrasound-guided core biopsy of peripheral nerve sheath tumors",
abstract = "Purpose To retrospectively evaluate the diagnostic accuracy of and complications from ultrasound-guided core needle biopsy (UGCNB) of suspected peripheral nerve sheath tumors (PNSTs). Methods Patients undergoing UGCNB from January 2004 to December 2016, based on the suspicion of PNST, were included in the study. Age, gender, anatomical location, dates of relevant events, and histopathological reports of the UGCNB cores and the resected tumors were retrieved from the patients' medical records. Results A total of 154 UGCNBs were identified. One hundred and forty (90.9%) of these resulted in a conclusive histopathological report, while 14 were unsuited for histopathological analysis due to insufficient amount of tissue and/or nonrepresentative tissue. The overall diagnostic accuracy of UGCNB with respect to discriminate malignant from benign tumors was 99.3%, while correct specific UGCNB diagnoses were confirmed in 95.1% of the cases. Sensitivity and specificity were 90.9% (95% CI: 58.7-99.8%) and 100% (95% CI: 97.2-100%), respectively. The positive predictive value was 100%, and the negative predictive value was 99.2%. Except for one patient, who reported mild dysesthesia, which resolved 2 days after the UGCNB, no complications were reported. Conclusion This study suggests that UGCNB is accurate and safe in patients suspected for PNST.",
keywords = "diagnostic accuracy, peripheral nerve sheath tumors, peripheral nerves, sonography, ultrasound-guided core needle biopsy, FINE-NEEDLE-ASPIRATION",
author = "Mikkel Tottrup and Eriksen, {Jacob D.} and Hellfritzsch, {Michel B.} and Sorensen, {Flemming B.} and Thomas Baad-Hansen",
year = "2020",
doi = "10.1002/jcu.22769",
language = "English",
volume = "48",
pages = "134--138",
journal = "Journal of Clinical Ultrasound",
issn = "0091-2751",
publisher = "JohnWiley & Sons, Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Diagnostic accuracy of ultrasound-guided core biopsy of peripheral nerve sheath tumors

AU - Tottrup, Mikkel

AU - Eriksen, Jacob D.

AU - Hellfritzsch, Michel B.

AU - Sorensen, Flemming B.

AU - Baad-Hansen, Thomas

PY - 2020

Y1 - 2020

N2 - Purpose To retrospectively evaluate the diagnostic accuracy of and complications from ultrasound-guided core needle biopsy (UGCNB) of suspected peripheral nerve sheath tumors (PNSTs). Methods Patients undergoing UGCNB from January 2004 to December 2016, based on the suspicion of PNST, were included in the study. Age, gender, anatomical location, dates of relevant events, and histopathological reports of the UGCNB cores and the resected tumors were retrieved from the patients' medical records. Results A total of 154 UGCNBs were identified. One hundred and forty (90.9%) of these resulted in a conclusive histopathological report, while 14 were unsuited for histopathological analysis due to insufficient amount of tissue and/or nonrepresentative tissue. The overall diagnostic accuracy of UGCNB with respect to discriminate malignant from benign tumors was 99.3%, while correct specific UGCNB diagnoses were confirmed in 95.1% of the cases. Sensitivity and specificity were 90.9% (95% CI: 58.7-99.8%) and 100% (95% CI: 97.2-100%), respectively. The positive predictive value was 100%, and the negative predictive value was 99.2%. Except for one patient, who reported mild dysesthesia, which resolved 2 days after the UGCNB, no complications were reported. Conclusion This study suggests that UGCNB is accurate and safe in patients suspected for PNST.

AB - Purpose To retrospectively evaluate the diagnostic accuracy of and complications from ultrasound-guided core needle biopsy (UGCNB) of suspected peripheral nerve sheath tumors (PNSTs). Methods Patients undergoing UGCNB from January 2004 to December 2016, based on the suspicion of PNST, were included in the study. Age, gender, anatomical location, dates of relevant events, and histopathological reports of the UGCNB cores and the resected tumors were retrieved from the patients' medical records. Results A total of 154 UGCNBs were identified. One hundred and forty (90.9%) of these resulted in a conclusive histopathological report, while 14 were unsuited for histopathological analysis due to insufficient amount of tissue and/or nonrepresentative tissue. The overall diagnostic accuracy of UGCNB with respect to discriminate malignant from benign tumors was 99.3%, while correct specific UGCNB diagnoses were confirmed in 95.1% of the cases. Sensitivity and specificity were 90.9% (95% CI: 58.7-99.8%) and 100% (95% CI: 97.2-100%), respectively. The positive predictive value was 100%, and the negative predictive value was 99.2%. Except for one patient, who reported mild dysesthesia, which resolved 2 days after the UGCNB, no complications were reported. Conclusion This study suggests that UGCNB is accurate and safe in patients suspected for PNST.

KW - diagnostic accuracy

KW - peripheral nerve sheath tumors

KW - peripheral nerves

KW - sonography

KW - ultrasound-guided core needle biopsy

KW - FINE-NEEDLE-ASPIRATION

U2 - 10.1002/jcu.22769

DO - 10.1002/jcu.22769

M3 - Journal article

C2 - 31441068

VL - 48

SP - 134

EP - 138

JO - Journal of Clinical Ultrasound

JF - Journal of Clinical Ultrasound

SN - 0091-2751

IS - 3

ER -