Psykologisk Institut

Development and preliminary validation of the Adolescent Psoriasis Quality of Life instrument (APso-QOL): a disease-specific measure of quality of life in adolescents with psoriasis

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

Background
No age‐appropriate and disease‐specific instrument currently exists to measure health‐related quality of life (HRQOL) in adolescents with psoriasis (12‐17 years).

Objectives
To develop and provide preliminary validation of the Adolescent Psoriasis Quality of Life instrument (APso‐QOL).

Methods
Qualitative interviews with adolescents with psoriasis, parents of adolescents with psoriasis, and health care professionals informed the development of an initial item pool for the APso‐QOL, which was subsequently refined through cognitive interviews. Finally, data from an independent sample of adolescents with psoriasis was used for item reduction, scale construction, and initial validation, using a combination of techniques from classical test theory and Rasch modelling.

Results
Rich qualitative data concerning HRQOL in adolescents with psoriasis (18 adolescents, 14 parents, and 4 health care professionals) combined with cognitive interview testing (n = 12) resulted in a 41‐item draft version. Item reduction led to the final APso‐QOL; a 17‐item instrument consisting of two subscales showing good fit to their respective Rasch models: Psychosocial Impact (APso‐PI; 12 items) and impact of Physical Symptoms and Treatment (APso‐PST; 5 items) (n=50). All a priori stated hypotheses regarding construct validity were supported. Both subscales and the total scale showed acceptable test‐retest reliabilities (intra‐class correlations 0.97, 0.89, and 0.96) and internal consistencies (Cronbach’s α 0.94, 0.81, and 0.95).

Conclusions
The preliminary form of the instrument APso‐QOL shows promising psychometric properties. It can be used in daily clinical practice and research to support a patient‐centered approach and inform treatment planning.
OriginalsprogEngelsk
TidsskriftBritish Journal of Dermatology
Vol/bind183
Nummer1
Sider (fra-til)96-104
Antal sider9
ISSN0007-0963
DOI
StatusUdgivet - jul. 2020

Bibliografisk note

© 2019 British Association of Dermatologists.

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