Day-to-day reliability, agreement and discriminative validity of measuring walking-related performance fatigability in persons with multiple sclerosis

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DOI

  • Fanny Van Geel, REVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences,Hasselt University, Diepenbeek, Belgium., Belgien
  • Renee Veldkamp, REVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences,Hasselt University, Diepenbeek, Belgium., Belgien
  • Deborah Severijns, Ter Heide, Genk, Belgium/Hasselt University, Diepenbeek, Belgium., Belgien
  • Ulrik Dalgas
  • Peter Feys, REVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences,Hasselt University, Diepenbeek, Belgium., Belgien

BACKGROUND: Day-to-day reliability and cut-off values to detect abnormal walking fatigability (WF) remain to be investigated in persons with multiple sclerosis (pwMS).

METHODS: In all, 49 pwMS (mean Expanded Disability Status Scale (EDSS) ± standard deviation (SD): 3.3 ± 1.9) and 28 matched healthy controls (HC) performed the six-minute walking test (6MWT) on two different days to determine day-to-day reliability (intraclass correlation coefficient (ICC)) and limits of agreement (LOA) for five different equations of WF.

OBJECTIVE: To examine day-to-day reliability, agreement and discriminative validity for measuring WF.

RESULTS AND CONCLUSION: WF expressed as the ratio between the first and sixth minute had the best day-to-day reliability (ICC's range of 0.76-0.95 and 0.60-0.86, respectively) in both pwMS and HC, while LOA were 15% and 7%, respectively. Ecological validity and clinical importance should be further investigated.

OriginalsprogEngelsk
Artikelnummer1352458519872465
TidsskriftMultiple sclerosis (Houndmills, Basingstoke, England)
Vol/bind26
Nummer13
Antal sider5
ISSN1352-4585
DOI
StatusUdgivet - nov. 2020

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