Dapsoninduceret fald i HbA1c kan give et falskt billede af diabeteskontrollen

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Abstract

Glycated haemoglobin (HbA(1c)) level is used to monitor glycaemic control in diabetic patients, and has recently been included as a diagnostic factor for type 2 diabetes mellitus (DM). A 50-year-old male with well-controlled type 1 DM, Mb Addison and coeliac disease was diagnosed with dermatitis herpetiformis and treated with dapsone. Subsequently, the patient presented a pronounced drop in HbA(1c) levels without changes in blood glucose levels. S-fructosamine values were in agreement with the previous stable HbA(1c) values. Blood analyses showed inappropriately low HbA(1c) values due to mild haemolysis and shortening of erythrocyte lifetime without anaemia.
Bidragets oversatte titelDapsone-induced decrease in the HbA(1c) level may cause artefacts in diabetic control
OriginalsprogDansk
TidsskriftUgeskrift for Læger
Vol/bind175
Nummer8
Sider (fra-til)505-6
Antal sider2
ISSN0041-5782
StatusUdgivet - 18 feb. 2013

Emneord

  • Anti-Infective Agents
  • Dapsone
  • Dermatitis Herpetiformis
  • Diabetes Mellitus, Type 1
  • Hemoglobin A, Glycosylated
  • Hemolysis
  • Humans
  • Male
  • Middle Aged

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