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Lung dysfunction causes significant mortality and morbidity and is a key organ in post-mortem investigation. Post-mortem (PM) medical imaging is being increasingly used, with computed tomography (CT) the most widespread modality. PMCT is used either as a supplement or an alternative to autopsy, especially in cases where autopsy is not possible or undesirable. Unfortunately, natural PM-processes in the lung obscure radiological interpretation in the dead, which accordingly is very different from the living. Interpretation of PMCT therefore requires special training and experience. The lung is also relatively difficult to examine during conventional autopsy, but diagnosis is improved by histological processing to allow ex vivo identification of infections and other pathological conditions. PMCT can examine the lung in-situ and is even superior to autopsy in certain aspects (especially for pneumothorax, small nodules and showing extent of abnormalities). Ventilated PMCT can be used to mimic clinical breath-hold procedures to improve overall pulmonary imaging quality.
Originalsprog | Engelsk |
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Artikelnummer | 100436 |
Tidsskrift | Current Opinion in Physiology |
Vol/bind | 22 |
Antal sider | 8 |
ISSN | 2468-8681 |
DOI | |
Status | Udgivet - aug. 2021 |
Funding Information:
N/A.
Publisher Copyright:
© 2021 Elsevier Ltd
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