CT-guided transarticular biopsy of the sacroiliac joint: Technique and histomorphological results. A preliminary study

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CT-guided transarticular biopsy of the sacroiliac joint : Technique and histomorphological results. A preliminary study. / Egund, Niels; Sørensen, Flemming Brandt; Østgård, René et al.

I: Skeletal Radiology, Bind 49, Nr. 3, 03.2020, s. 453-460.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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@article{4fa999f8d9164461aa0717de54cac971,
title = "CT-guided transarticular biopsy of the sacroiliac joint: Technique and histomorphological results. A preliminary study",
abstract = "Objective: To introduce and evaluate computed tomography (CT)-guided transarticular needle biopsy of the cartilaginous sacroiliac joint (SIJ) and to assess the biopsy results microscopically. Materials and methods: The new CT-guided transarticular biopsy of the SIJ was performed in a young corpse and ten patients, two males and eight females aged 18–81 years. All patients had abnormal findings by magnetic resonance imaging (MRI) of the SIJs, including bone marrow edema, related to different types of joint disorders. The biopsies were focused on areas with bone marrow edema. The quality of the specimens obtained, using two different types of biopsy needles, was assessed microscopically. Results: Biopsies containing cartilage, subchondral plate, and bone marrow from the iliac and sacral sides were obtained from the corpse and three patients and from the iliac bone only in two patients. In three patients, the biopsy needles could not penetrate the bone marrow to the joint facet due to pronounced subchondral sclerosis, but adequate marrow biopsies were obtained. Two biopsies were inadequate, one due to technical problems and one was crushed during preparation. Histological assessment of eight adequate specimens revealed inflammatory bone marrow changes, except in two specimens from females with pronounced sclerosis conforming to osteitis condensans ilii. Conclusions: Transarticular SIJ biopsies are obtainable and can be directed towards areas with MRI abnormalities. They can be used to confirm inflammatory changes histologically. With the biopsy needles used, severe bone marrow sclerosis may hinder penetration to the cartilage, but bone marrow specimens can be obtained.",
keywords = "Biopsy, Computed tomography, Histopathology, Sacroiliac joints, Spondyloarthritis",
author = "Niels Egund and S{\o}rensen, {Flemming Brandt} and Ren{\'e} {\O}stg{\aa}rd and Loft, {Anne Gitte} and Boel, {Lene Warner Thorup} and Jurik, {Anne Grethe}",
year = "2020",
month = mar,
doi = "10.1007/s00256-019-03305-x",
language = "English",
volume = "49",
pages = "453--460",
journal = "Skeletal Radiology",
issn = "0364-2348",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - CT-guided transarticular biopsy of the sacroiliac joint

T2 - Technique and histomorphological results. A preliminary study

AU - Egund, Niels

AU - Sørensen, Flemming Brandt

AU - Østgård, René

AU - Loft, Anne Gitte

AU - Boel, Lene Warner Thorup

AU - Jurik, Anne Grethe

PY - 2020/3

Y1 - 2020/3

N2 - Objective: To introduce and evaluate computed tomography (CT)-guided transarticular needle biopsy of the cartilaginous sacroiliac joint (SIJ) and to assess the biopsy results microscopically. Materials and methods: The new CT-guided transarticular biopsy of the SIJ was performed in a young corpse and ten patients, two males and eight females aged 18–81 years. All patients had abnormal findings by magnetic resonance imaging (MRI) of the SIJs, including bone marrow edema, related to different types of joint disorders. The biopsies were focused on areas with bone marrow edema. The quality of the specimens obtained, using two different types of biopsy needles, was assessed microscopically. Results: Biopsies containing cartilage, subchondral plate, and bone marrow from the iliac and sacral sides were obtained from the corpse and three patients and from the iliac bone only in two patients. In three patients, the biopsy needles could not penetrate the bone marrow to the joint facet due to pronounced subchondral sclerosis, but adequate marrow biopsies were obtained. Two biopsies were inadequate, one due to technical problems and one was crushed during preparation. Histological assessment of eight adequate specimens revealed inflammatory bone marrow changes, except in two specimens from females with pronounced sclerosis conforming to osteitis condensans ilii. Conclusions: Transarticular SIJ biopsies are obtainable and can be directed towards areas with MRI abnormalities. They can be used to confirm inflammatory changes histologically. With the biopsy needles used, severe bone marrow sclerosis may hinder penetration to the cartilage, but bone marrow specimens can be obtained.

AB - Objective: To introduce and evaluate computed tomography (CT)-guided transarticular needle biopsy of the cartilaginous sacroiliac joint (SIJ) and to assess the biopsy results microscopically. Materials and methods: The new CT-guided transarticular biopsy of the SIJ was performed in a young corpse and ten patients, two males and eight females aged 18–81 years. All patients had abnormal findings by magnetic resonance imaging (MRI) of the SIJs, including bone marrow edema, related to different types of joint disorders. The biopsies were focused on areas with bone marrow edema. The quality of the specimens obtained, using two different types of biopsy needles, was assessed microscopically. Results: Biopsies containing cartilage, subchondral plate, and bone marrow from the iliac and sacral sides were obtained from the corpse and three patients and from the iliac bone only in two patients. In three patients, the biopsy needles could not penetrate the bone marrow to the joint facet due to pronounced subchondral sclerosis, but adequate marrow biopsies were obtained. Two biopsies were inadequate, one due to technical problems and one was crushed during preparation. Histological assessment of eight adequate specimens revealed inflammatory bone marrow changes, except in two specimens from females with pronounced sclerosis conforming to osteitis condensans ilii. Conclusions: Transarticular SIJ biopsies are obtainable and can be directed towards areas with MRI abnormalities. They can be used to confirm inflammatory changes histologically. With the biopsy needles used, severe bone marrow sclerosis may hinder penetration to the cartilage, but bone marrow specimens can be obtained.

KW - Biopsy

KW - Computed tomography

KW - Histopathology

KW - Sacroiliac joints

KW - Spondyloarthritis

UR - http://www.scopus.com/inward/record.url?scp=85071762300&partnerID=8YFLogxK

U2 - 10.1007/s00256-019-03305-x

DO - 10.1007/s00256-019-03305-x

M3 - Journal article

C2 - 31485679

AN - SCOPUS:85071762300

VL - 49

SP - 453

EP - 460

JO - Skeletal Radiology

JF - Skeletal Radiology

SN - 0364-2348

IS - 3

ER -