Controlling the morphology of microgels by ionic stimuli

Maxime J. Bergman; Jan S. Pedersen; Peter Schurtenberger; Niels Boon

doi:10.1039/c9sm02170a

Controlling the morphology of microgels by ionic stimuli

Maxime J. Bergman, Jan S. Pedersen, Peter Schurtenberger, Niels Boon^*

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

24 Citationer (Scopus)

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Abstract

Stimuli-responsive microgels have attracted much interest for their use as vehicles for drug delivery or as the building blocks of adaptive materials. Ionic microgel particles, including popular poly(NIPAM-co-acrylic acid), show strong mechanical responsiveness to many external stimuli, including changes in ionic strength or acidity. In this work, we demonstrate that combining multiple ionic stimuli can enable detailed control over the morphology of microgels. To this extent, we analyze the particle morphology in various surroundings with light-scattering techniques. First, we find strong indications of an inverted density profile in the core of the particles. Secondly, we show that the swelling of this hydrogel core and the corona of dangling polymer ends can be targeted separately by a combination of deionization and deprotonation steps. Hence, this work represents an advance in tailoring particle morphologies after synthesis in a predictable fashion.

Originalsprog	Engelsk
Tidsskrift	Soft Matter
Vol/bind	16
Nummer	11
Sider (fra-til)	2786-2794
Antal sider	9
ISSN	1744-683X
DOI	https://doi.org/10.1039/c9sm02170a
Status	Udgivet - 2020

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10.1039/c9sm02170aLicens: CC BY-NC

c9sm02170aForlagets udgivne version, 2,76 MBLicens: CC BY-NC

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Citationsformater

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T1 - Controlling the morphology of microgels by ionic stimuli

AU - Bergman, Maxime J.

AU - Pedersen, Jan S.

AU - Schurtenberger, Peter

AU - Boon, Niels

PY - 2020

Y1 - 2020

N2 - Stimuli-responsive microgels have attracted much interest for their use as vehicles for drug delivery or as the building blocks of adaptive materials. Ionic microgel particles, including popular poly(NIPAM-co-acrylic acid), show strong mechanical responsiveness to many external stimuli, including changes in ionic strength or acidity. In this work, we demonstrate that combining multiple ionic stimuli can enable detailed control over the morphology of microgels. To this extent, we analyze the particle morphology in various surroundings with light-scattering techniques. First, we find strong indications of an inverted density profile in the core of the particles. Secondly, we show that the swelling of this hydrogel core and the corona of dangling polymer ends can be targeted separately by a combination of deionization and deprotonation steps. Hence, this work represents an advance in tailoring particle morphologies after synthesis in a predictable fashion.

AB - Stimuli-responsive microgels have attracted much interest for their use as vehicles for drug delivery or as the building blocks of adaptive materials. Ionic microgel particles, including popular poly(NIPAM-co-acrylic acid), show strong mechanical responsiveness to many external stimuli, including changes in ionic strength or acidity. In this work, we demonstrate that combining multiple ionic stimuli can enable detailed control over the morphology of microgels. To this extent, we analyze the particle morphology in various surroundings with light-scattering techniques. First, we find strong indications of an inverted density profile in the core of the particles. Secondly, we show that the swelling of this hydrogel core and the corona of dangling polymer ends can be targeted separately by a combination of deionization and deprotonation steps. Hence, this work represents an advance in tailoring particle morphologies after synthesis in a predictable fashion.

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DO - 10.1039/c9sm02170a

M3 - Journal article

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VL - 16

SP - 2786

EP - 2794

JO - Soft Matter

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Controlling the morphology of microgels by ionic stimuli

Abstract

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