Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

DOI

  • Ilona A. Dekkers, Leiden University Medical Center
  • ,
  • Anneloes de Boer, Utrecht University
  • ,
  • Kaniska Sharma, Leeds University
  • ,
  • Eleanor F. Cox, University of Nottingham
  • ,
  • Hildo J. Lamb, Leiden University Medical Center
  • ,
  • David L. Buckley, Leeds University
  • ,
  • Octavia Bane, Icahn School of Medicine at Mount Sinai
  • ,
  • David M. Morris, Edinburgh University
  • ,
  • Pottumarthi V. Prasad, NorthShore University Health System
  • ,
  • Scott I.K. Semple, Edinburgh University
  • ,
  • Keith A. Gillis, University of Glasgow
  • ,
  • Paul Hockings, Antaros Medical, Chalmers University of Technology
  • ,
  • Charlotte Buchanan, University of Nottingham
  • ,
  • Marcos Wolf, Medical University of Vienna
  • ,
  • Christoffer Laustsen
  • Tim Leiner, Utrecht University
  • ,
  • Bryan Haddock, Rigshospitalet
  • ,
  • Johannes M. Hoogduin, Utrecht University
  • ,
  • Pim Pullens, Ghent University Hospital, Ghent, Universiteit Gent
  • ,
  • Steven Sourbron, Leeds University
  • ,
  • Susan Francis, Utrecht University

To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and T2 mapping participated in a consensus project, which was initiated by the European Cooperation in Science and Technology Action PARENCHIMA CA16103. Consensus recommendations were formulated using a two-step modified Delphi method. The first survey consisted of 56 items on T1 mapping, of which 4 reached the pre-defined consensus threshold of 75% or higher. The second survey was expanded to include both T1 and T2 mapping, and consisted of 54 items of which 32 reached consensus. Recommendations based were formulated on hardware, patient preparation, acquisition, analysis and reporting. Consensus-based technical recommendations for renal T1 and T2 mapping were formulated. However, there was considerable lack of consensus for renal T1 and particularly renal T2 mapping, to some extent surprising considering the long history of relaxometry in MRI, highlighting key knowledge gaps that require further work. This paper should be regarded as a first step in a long-term evidence-based iterative process towards ever increasing harmonization of scan protocols across sites, to ultimately facilitate clinical implementation.

OriginalsprogEngelsk
TidsskriftMagnetic Resonance Materials in Physics, Biology and Medicine
Vol/bind33
Nummer1
Sider (fra-til)163–176
Antal sider14
ISSN0968-5243
DOI
StatusUdgivet - feb. 2020

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