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Computer-Aided Design and Production of RNA Origami as Protein Scaffolds and Biosensors

Publikation: Bidrag til bog/antologi/rapport/proceedingBidrag til bog/antologiForskning


RNA nanotechnology is able to take advantage of the modularity of RNA to build a wide variety of structures and functional devices from a common set of structural modules. The RNA origami architecture harnesses the property of RNA to fold as it is being enzymatically synthesized by the RNA polymerase and enables the design of single-stranded devices that integrate multiple structural and functional RNA motifs. Here, we provide detailed procedures on how to design and characterize RNA origami structures. The process is illustrated by two examples: one that forms lattices and another example that acts as biosensors.

TitelDNA and RNA Origami : Methods and protocols
RedaktørerJulián Valero
Antal sider17
ForlagHumana Press
ISBN (trykt)978-1-0716-3027-3
ISBN (Elektronisk)978-1-0716-3028-0
StatusUdgivet - 2023
SerietitelMethods in Molecular Biology

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