Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study

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  • Jessica E Laine, Imperial College London, University of Bern, Storbritannien
  • Inge Huybrechts, WHO International Agency for Research on Cancer, Frankrig
  • Marc J Gunter, WHO International Agency for Research on Cancer
  • ,
  • Pietro Ferrari, WHO International Agency for Research on Cancer, Frankrig
  • Elisabete Weiderpass, WHO International Agency for Research on Cancer, Frankrig
  • Kostas Tsilidis, Imperial Coll London, Imperial College London, UKDRI, Storbritannien
  • Dagfinn Aune, Imperial College London, Bjørknes University College, Oslo University Hospital, Storbritannien
  • Matthias B Schulze, Institute of Nutritional Sciences, University of Potsdam, Nuthetal, Germany., Tyskland
  • Manuela Bergmann, German Institute of Human Nutrition Potsdam-Rehbruecke, Potsdam, Germany., Tyskland
  • Elisabeth H M Temme, National Institute for Public Health and the Environment (RIVM), Bilthoven, Holland
  • Jolanda M A Boer, National Institute for Public Health and the Environment (RIVM), Holland
  • Claudia Agnoli, Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, 1, 20133 Milano, Italy., Italien
  • Ulrika Ericson, Lund University, Malmö, Sverige
  • Anna Stubbendorff, Lund University, Malmö, Sverige
  • Daniel B Ibsen
  • Christina Catherine Dahm
  • Mélanie Deschasaux, Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Nutritional Epidemiology Research Team (EREN), Epidemiology and Statistics Research Center-University of Paris (CRESS), Bobigny, Frankrig
  • Mathilde Touvier, Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Nutritional Epidemiology Research Team (EREN), Epidemiology and Statistics Research Center-University of Paris (CRESS), Bobigny, Frankrig
  • Emmanuelle Kesse-Guyot, Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Nutritional Epidemiology Research Team (EREN), Epidemiology and Statistics Research Center-University of Paris (CRESS), Bobigny, Frankrig
  • Maria-Jose Sánchez Pérez, Escuela Andaluza de Salud Pública (EASP), Granada, Instituto de Investigación Biosanitaria (ibs.GRANADA), CIBER Epidemiology and Public Health (CIBERESP), Madrid, University of Granada, Spanien
  • Miguel Rodríguez Barranco, Escuela Andaluza de Salud Pública (EASP), Granada, Instituto de Investigación Biosanitaria (ibs.GRANADA), CIBER Epidemiology and Public Health CIBERESP, University of Granada, Spanien
  • Tammy Y N Tong, University of Oxford, Storbritannien
  • Keren Papier, University of Oxford, Storbritannien
  • Anika Knuppel, University of Oxford, Storbritannien
  • Marie-Christine Boutron-Ruault, CESP, INSERM U1018, Univ. Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif Cedex, France., Spanien
  • Francesca Mancini, CESP, INSERM U1018, Univ. Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif Cedex, France., Frankrig
  • Gianluca Severi, University of Florence, Florence, CESP, INSERM U1018, Univ. Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif Cedex, France., Gustave Roussy, Frankrig
  • Bernard Srour, German Cancer Rsearch Center Heidelberg, Tyskland
  • Tilman Kühn, German Cancer Rsearch Center Heidelberg, Tyskland
  • Giovanna Masala, Institute for Cancer Research, Italien
  • Antonio Agudo, Catalan Institute of Oncology-ICO, Spanien
  • Guri Skeie, Arctic University of Norway, Tromsø, Norway, Norge
  • Charlotta Rylander, Arctic University of Norway, Tromsø, Norway, Norge
  • Torkjel M Sandanger, Arctic University of Norway, Tromsø, Norway, Norge
  • Elio Riboli, Imperial Coll London, Imperial College London, UKDRI, Storbritannien
  • Paolo Vineis, Imperial Coll London, Imperial College London, UKDRI, Italian Institute of Technology, Genova, Storbritannien

BACKGROUND: Unhealthy diets, the rise of non-communicable diseases, and the declining health of the planet are highly intertwined, where food production and consumption are major drivers of increases in greenhouse gas emissions, substantial land use, and adverse health such as cancer and mortality. To assess the potential co-benefits from shifting to more sustainable diets, we aimed to investigate the associations of dietary greenhouse gas emissions and land use with all-cause and cause-specific mortality and cancer incidence rates.

METHODS: Using data from 443 991 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, a multicentre prospective cohort, we estimated associations between dietary contributions to greenhouse gas emissions and land use and all-cause and cause-specific mortality and incident cancers using Cox proportional hazards regression models. The main exposures were modelled as quartiles. Co-benefits, encompassing the potential effects of alternative diets on all-cause mortality and cancer and potential reductions in greenhouse gas emissions and land use, were estimated with counterfactual attributable fraction intervention models, simulating potential effects of dietary shifts based on the EAT-Lancet reference diet.

FINDINGS: In the pooled analysis, there was an association between levels of dietary greenhouse gas emissions and all-cause mortality (adjusted hazard ratio [HR] 1·13 [95% CI 1·10-1·16]) and between land use and all-cause mortality (1·18 [1·15-1·21]) when comparing the fourth quartile to the first quartile. Similar associations were observed for cause-specific mortality. Associations were also observed between all-cause cancer incidence rates and greenhouse gas emissions, when comparing the fourth quartile to the first quartile (adjusted HR 1·11 [95% CI 1·09-1·14]) and between all-cause cancer incidence rates and land use (1·13 [1·10-1·15]); however, estimates differed by cancer type. Through counterfactual attributable fraction modelling of shifts in levels of adherence to the EAT-Lancet diet, we estimated that up to 19-63% of deaths and up to 10-39% of cancers could be prevented, in a 20-year risk period, by different levels of adherence to the EAT-Lancet reference diet. Additionally, switching from lower adherence to the EAT-Lancet reference diet to higher adherence could potentially reduce food-associated greenhouse gas emissions up to 50% and land use up to 62%.

INTERPRETATION: Our results indicate that shifts towards universally sustainable diets could lead to co-benefits, such as minimising diet-related greenhouse gas emissions and land use, reducing the environmental footprint, aiding in climate change mitigation, and improving population health.

FUNDING: European Commission (DG-SANCO), the International Agency for Research on Cancer (IARC), MRC Early Career Fellowship (MR/M501669/1).

OriginalsprogEngelsk
TidsskriftThe Lancet Planetary Health
Vol/bind5
Nummer11
Sider (fra-til)e786-e796
Antal sider11
ISSN2542-5196
DOI
StatusUdgivet - nov. 2021

Bibliografisk note

© 2021 International Agency for Research on Cancer; licensee Elsevier. This is an Open Access article published under the CC BY 3.0 IGO license which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any use of this article, there should be no suggestion that IARC endorses any specific organisation, products or services. The use of the IARC logo is not permitted. This notice should be preserved along with the article's original URL.

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