Chronic oral disease burden at the first 1000 days: Intergenerational risk factors, BRISA cohort

  • Sângela Maria Pereira Araújo
  • , Gustavo G. Nascimento
  • , Lorena Lucia Costa Ladeira
  • , Silas Alves-Costa
  • , Maria Conceição Saraiva
  • , Claudia Maria Coelho Alves
  • , Erika Bárbara Abreu Fonseca Thomaz
  • , Cecilia Claudia Costa Ribeiro*
  • *Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

1 Citationer (Scopus)

Abstract

Objective: To analyze multiple-causal models, including socioeconomic, obesity, sugar consumption, alcohol smoking, caries, and periodontitis variables in pregnant women with early sugar exposure, obesity, and the Chronic Oral Disease Burden in their offspring around the first 1000 days of life. Methods: The BRISA cohort study, Brazil, had two assessments: at the 22nd–25th gestational weeks and during the child's second year (n = 1141). We proposed a theoretical model exploring the association between socioeconomic and pregnancy factors (age, smoking, alcohol, sugars, obesity, periodontitis, and caries) and child's variables (sugars and overweight) with the outcome, Chronic Oral Disease Burden (latent variable deduced from visible plaque, gingivitis, and tooth decay), using structural equation modeling. Results: Caries and periodontitis were correlated in pregnant women. Addictive behaviors in the gestational period were correlated. Obesity (Standardized coefficient - SC = 0.081; p = 0.047) and added sugar consumption (SC = 0.142; p = 0.041) were observed intergenerationally in the pregnant woman-child dyads. Sugar consumption by the children (SC = 0.210; p = 0.041) increased the Chronic Oral Disease Burden. Conclusions: Poor caries and periodontal indicators were correlated in pregnant women and their offspring. Obesity and sugar consumption act intergenerationally. Oral health in early life may change life trajectory since the worst oral conditions predict main NCDs.

OriginalsprogEngelsk
TidsskriftOral Diseases
Vol/bind30
Nummer8
Sider (fra-til)5388-5396
Antal sider9
ISSN1354-523X
DOI
StatusUdgivet - nov. 2024

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