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Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging

Publikation: KonferencebidragPosterForskningpeer review

Standard

Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging. / Frøkjær, Jens Brøndum; Olesen, Søren Schou; Gram, Mikkel; Yavarian, Yousef; Drewes, Asbjørn Mohr.

2011. Poster session præsenteret ved 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII, Hamburg, Tyskland.

Publikation: KonferencebidragPosterForskningpeer review

Harvard

Frøkjær, JB, Olesen, SS, Gram, M, Yavarian, Y & Drewes, AM 2011, 'Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging', 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII, Hamburg, Tyskland, 21/09/2011 - 24/09/2011.

APA

Frøkjær, J. B., Olesen, S. S., Gram, M., Yavarian, Y., & Drewes, A. M. (2011). Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging. Poster session præsenteret ved 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII, Hamburg, Tyskland.

CBE

Frøkjær JB, Olesen SS, Gram M, Yavarian Y, Drewes AM. 2011. Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging. Poster session præsenteret ved 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII, Hamburg, Tyskland.

MLA

Frøkjær, Jens Brøndum o.a.. Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging. 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII, 21 sep. 2011, Hamburg, Tyskland, Poster, 2011.

Vancouver

Frøkjær JB, Olesen SS, Gram M, Yavarian Y, Drewes AM. Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging. 2011. Poster session præsenteret ved 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII, Hamburg, Tyskland.

Author

Frøkjær, Jens Brøndum ; Olesen, Søren Schou ; Gram, Mikkel ; Yavarian, Yousef ; Drewes, Asbjørn Mohr. / Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging. Poster session præsenteret ved 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII, Hamburg, Tyskland.

Bibtex

@conference{a4a2ccf38b884404ba5ea03d25edbbd0,
title = "Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging",
abstract = "Objective In patients with painful chronic pancreatitis (CP) there is increasing evidence of abnormal pain processing in the central nervous system. Using magnetic resonance (MR) diffusion tensor imaging, brain microstructure in areas involved in processing of visceral pain was characterised and these findings were correlated to clinical pain scores. Methods 23 patients with CP pain and 14 controls were studied in a 3T MR scanner. Apparent diffusion coefficient (ADC) (ie, diffusivity of water) and fractional anisotropy (FA) (ie, organisation of fibres) values were assessed in the amygdala, cingulate cortex, insula, prefrontal cortex and secondary sensory cortex. Daily pain scores and the Brief Pain Inventory Short Form were collected 1 week before the investigation. Results In grey matter, patients had increased ADC values in amygdala, cingulate cortex, insula and prefrontal cortex, as well as decreased FA values in cingulate cortex and secondary sensory cortex. In white matter, patients had increased ADC values in insula and prefrontal cortex, and decreased FA values in insula and prefrontal cortex (all p values 0.05). Microstructural changes in cingulate and prefrontal cortices were correlated to patients' clinical pain scores. Conclusion The findings suggest that microstructural changes of the brain accompany pain in CP. The changes are likely to be a consequence of ongoing pain and structural reorganisation of the neuromatrix as also seen in other diseases characterised by chronic pain.",
author = "Fr{\o}kj{\ae}r, {Jens Br{\o}ndum} and Olesen, {S{\o}ren Schou} and Mikkel Gram and Yousef Yavarian and Drewes, {Asbj{\o}rn Mohr}",
year = "2011",
language = "English",
note = "null ; Conference date: 21-09-2011 Through 24-09-2011",

}

RIS

TY - CONF

T1 - Changes of brain microstructure in patients with painful chronic pancreatitis assessed by diffusion tensor imaging

AU - Frøkjær, Jens Brøndum

AU - Olesen, Søren Schou

AU - Gram, Mikkel

AU - Yavarian, Yousef

AU - Drewes, Asbjørn Mohr

PY - 2011

Y1 - 2011

N2 - Objective In patients with painful chronic pancreatitis (CP) there is increasing evidence of abnormal pain processing in the central nervous system. Using magnetic resonance (MR) diffusion tensor imaging, brain microstructure in areas involved in processing of visceral pain was characterised and these findings were correlated to clinical pain scores. Methods 23 patients with CP pain and 14 controls were studied in a 3T MR scanner. Apparent diffusion coefficient (ADC) (ie, diffusivity of water) and fractional anisotropy (FA) (ie, organisation of fibres) values were assessed in the amygdala, cingulate cortex, insula, prefrontal cortex and secondary sensory cortex. Daily pain scores and the Brief Pain Inventory Short Form were collected 1 week before the investigation. Results In grey matter, patients had increased ADC values in amygdala, cingulate cortex, insula and prefrontal cortex, as well as decreased FA values in cingulate cortex and secondary sensory cortex. In white matter, patients had increased ADC values in insula and prefrontal cortex, and decreased FA values in insula and prefrontal cortex (all p values 0.05). Microstructural changes in cingulate and prefrontal cortices were correlated to patients' clinical pain scores. Conclusion The findings suggest that microstructural changes of the brain accompany pain in CP. The changes are likely to be a consequence of ongoing pain and structural reorganisation of the neuromatrix as also seen in other diseases characterised by chronic pain.

AB - Objective In patients with painful chronic pancreatitis (CP) there is increasing evidence of abnormal pain processing in the central nervous system. Using magnetic resonance (MR) diffusion tensor imaging, brain microstructure in areas involved in processing of visceral pain was characterised and these findings were correlated to clinical pain scores. Methods 23 patients with CP pain and 14 controls were studied in a 3T MR scanner. Apparent diffusion coefficient (ADC) (ie, diffusivity of water) and fractional anisotropy (FA) (ie, organisation of fibres) values were assessed in the amygdala, cingulate cortex, insula, prefrontal cortex and secondary sensory cortex. Daily pain scores and the Brief Pain Inventory Short Form were collected 1 week before the investigation. Results In grey matter, patients had increased ADC values in amygdala, cingulate cortex, insula and prefrontal cortex, as well as decreased FA values in cingulate cortex and secondary sensory cortex. In white matter, patients had increased ADC values in insula and prefrontal cortex, and decreased FA values in insula and prefrontal cortex (all p values 0.05). Microstructural changes in cingulate and prefrontal cortices were correlated to patients' clinical pain scores. Conclusion The findings suggest that microstructural changes of the brain accompany pain in CP. The changes are likely to be a consequence of ongoing pain and structural reorganisation of the neuromatrix as also seen in other diseases characterised by chronic pain.

M3 - Poster

Y2 - 21 September 2011 through 24 September 2011

ER -