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Cardiovascular disease among people with drug use disorders

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Cardiovascular disease among people with drug use disorders. / Thylstrup, Birgitte; Clausen, Thomas; Hesse, Morten.

I: International Journal of Public Health (Print Edition), Bind 60, Nr. 6, 09.2015, s. 659-668.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Thylstrup, B, Clausen, T & Hesse, M 2015, 'Cardiovascular disease among people with drug use disorders', International Journal of Public Health (Print Edition), bind 60, nr. 6, s. 659-668. https://doi.org/10.1007/s00038-015-0698-3

APA

Thylstrup, B., Clausen, T., & Hesse, M. (2015). Cardiovascular disease among people with drug use disorders. International Journal of Public Health (Print Edition), 60(6), 659-668. https://doi.org/10.1007/s00038-015-0698-3

CBE

Thylstrup B, Clausen T, Hesse M. 2015. Cardiovascular disease among people with drug use disorders. International Journal of Public Health (Print Edition). 60(6):659-668. https://doi.org/10.1007/s00038-015-0698-3

MLA

Thylstrup, Birgitte, Thomas Clausen, og Morten Hesse. "Cardiovascular disease among people with drug use disorders". International Journal of Public Health (Print Edition). 2015, 60(6). 659-668. https://doi.org/10.1007/s00038-015-0698-3

Vancouver

Thylstrup B, Clausen T, Hesse M. Cardiovascular disease among people with drug use disorders. International Journal of Public Health (Print Edition). 2015 sep;60(6):659-668. https://doi.org/10.1007/s00038-015-0698-3

Author

Thylstrup, Birgitte ; Clausen, Thomas ; Hesse, Morten. / Cardiovascular disease among people with drug use disorders. I: International Journal of Public Health (Print Edition). 2015 ; Bind 60, Nr. 6. s. 659-668.

Bibtex

@article{caedfc5600ad4f868d1591b89b3d4da1,
title = "Cardiovascular disease among people with drug use disorders",
abstract = " Objectives To present the prevalence and incidence of cardiovascular disease (CVD) in a national cohort of patients seeking treatment for drug use disorders (DUD). Methods This is a longitudinal record linkage study of consecutive DUD treatment admissions between 2000 and 2006 from Denmark. Results Of 17,642 patients seeking treatment for DUD, 828 individuals (4.53 %) had a history of CVD at treatment entry. Among the remaining patients, 16,820 were traced and 1535 new incident cases of CVD were observed during a mean follow-up time of 7.5 years. The incidence of CVD was associated with intravenous drug use [subhazard ratio (SHR) = 1.41, p < 0.001], not responding to injection question (SHR = 1.23, p = 0.005), older age (SHR = 1.04 per year, p = 0.000), use of prescription methadone (SHR = 1.32, p < 0.001), use of benzodiazepines (SHR = 1.21, p = 0.005), and being referred to methadone treatment (SHR = 1.15, p = 0.022). The use of amphetamines was negatively associated with the risk of CVD within this cohort (SHR = 0.75, p = 0.001). Conclusions Patients injecting drugs using prescribed methadone were at elevated risk for cardiovascular disease and should be monitored for CVD. Opioid medications should be evaluated in terms of their cardiovascular sequelae. ",
author = "Birgitte Thylstrup and Thomas Clausen and Morten Hesse",
year = "2015",
month = sep,
doi = "10.1007/s00038-015-0698-3",
language = "English",
volume = "60",
pages = "659--668",
journal = "International Journal of Public Health (Print Edition)",
issn = "1661-8556",
publisher = "Springer Basel AG",
number = "6",

}

RIS

TY - JOUR

T1 - Cardiovascular disease among people with drug use disorders

AU - Thylstrup, Birgitte

AU - Clausen, Thomas

AU - Hesse, Morten

PY - 2015/9

Y1 - 2015/9

N2 - Objectives To present the prevalence and incidence of cardiovascular disease (CVD) in a national cohort of patients seeking treatment for drug use disorders (DUD). Methods This is a longitudinal record linkage study of consecutive DUD treatment admissions between 2000 and 2006 from Denmark. Results Of 17,642 patients seeking treatment for DUD, 828 individuals (4.53 %) had a history of CVD at treatment entry. Among the remaining patients, 16,820 were traced and 1535 new incident cases of CVD were observed during a mean follow-up time of 7.5 years. The incidence of CVD was associated with intravenous drug use [subhazard ratio (SHR) = 1.41, p < 0.001], not responding to injection question (SHR = 1.23, p = 0.005), older age (SHR = 1.04 per year, p = 0.000), use of prescription methadone (SHR = 1.32, p < 0.001), use of benzodiazepines (SHR = 1.21, p = 0.005), and being referred to methadone treatment (SHR = 1.15, p = 0.022). The use of amphetamines was negatively associated with the risk of CVD within this cohort (SHR = 0.75, p = 0.001). Conclusions Patients injecting drugs using prescribed methadone were at elevated risk for cardiovascular disease and should be monitored for CVD. Opioid medications should be evaluated in terms of their cardiovascular sequelae.

AB - Objectives To present the prevalence and incidence of cardiovascular disease (CVD) in a national cohort of patients seeking treatment for drug use disorders (DUD). Methods This is a longitudinal record linkage study of consecutive DUD treatment admissions between 2000 and 2006 from Denmark. Results Of 17,642 patients seeking treatment for DUD, 828 individuals (4.53 %) had a history of CVD at treatment entry. Among the remaining patients, 16,820 were traced and 1535 new incident cases of CVD were observed during a mean follow-up time of 7.5 years. The incidence of CVD was associated with intravenous drug use [subhazard ratio (SHR) = 1.41, p < 0.001], not responding to injection question (SHR = 1.23, p = 0.005), older age (SHR = 1.04 per year, p = 0.000), use of prescription methadone (SHR = 1.32, p < 0.001), use of benzodiazepines (SHR = 1.21, p = 0.005), and being referred to methadone treatment (SHR = 1.15, p = 0.022). The use of amphetamines was negatively associated with the risk of CVD within this cohort (SHR = 0.75, p = 0.001). Conclusions Patients injecting drugs using prescribed methadone were at elevated risk for cardiovascular disease and should be monitored for CVD. Opioid medications should be evaluated in terms of their cardiovascular sequelae.

U2 - 10.1007/s00038-015-0698-3

DO - 10.1007/s00038-015-0698-3

M3 - Journal article

C2 - 26104131

VL - 60

SP - 659

EP - 668

JO - International Journal of Public Health (Print Edition)

JF - International Journal of Public Health (Print Edition)

SN - 1661-8556

IS - 6

ER -