Brain capillary pericytes and neurovascular coupling

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DOI

  • Søren Grubb, Københavns Universitet
  • ,
  • Martin Lauritzen, Københavns Universitet, Rigshospitalet
  • ,
  • Christian Aalkjær

The neurovascular coupling ensures that cerebral activity is matched by the relevant blood flow. The control of the blood flow is mediated by capillaries and by the precapillary aterioles. It is the tone of the mural cells, which include pericytes, smooth muscle cells and cells with intermediate phenotypes between pericytes and smooth muscle cells, that determine the the diameter of the blood vessels and consequently the flow. Here we discuss the structure of these blood vessels and the excitationcontraction coupling of the mural cells.

OriginalsprogEngelsk
Artikelnummer110893
TidsskriftComparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
Vol/bind254
Antal sider7
ISSN1095-6433
DOI
StatusUdgivet - apr. 2021

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