Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy: Experience from the Nordic ARVC Registry

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy : Experience from the Nordic ARVC Registry. / Baturova, Maria A; Haugaa, Kristina H; Jensen, Henrik K; Svensson, Anneli; Gilljam, Thomas; Bundgaard, Henning; Madsen, Trine; Hansen, Jim; Chivulescu, Monica; Christiansen, Morten Krogh; Carlson, Jonas; Edvardsen, Thor; Svendsen, Jesper H; Platonov, Pyotr G.

I: International Journal of Cardiology, Bind 298, 01.2020, s. 39-43.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Baturova, MA, Haugaa, KH, Jensen, HK, Svensson, A, Gilljam, T, Bundgaard, H, Madsen, T, Hansen, J, Chivulescu, M, Christiansen, MK, Carlson, J, Edvardsen, T, Svendsen, JH & Platonov, PG 2020, 'Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy: Experience from the Nordic ARVC Registry', International Journal of Cardiology, bind 298, s. 39-43. https://doi.org/10.1016/j.ijcard.2019.07.086

APA

Baturova, M. A., Haugaa, K. H., Jensen, H. K., Svensson, A., Gilljam, T., Bundgaard, H., Madsen, T., Hansen, J., Chivulescu, M., Christiansen, M. K., Carlson, J., Edvardsen, T., Svendsen, J. H., & Platonov, P. G. (2020). Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy: Experience from the Nordic ARVC Registry. International Journal of Cardiology, 298, 39-43. https://doi.org/10.1016/j.ijcard.2019.07.086

CBE

Baturova MA, Haugaa KH, Jensen HK, Svensson A, Gilljam T, Bundgaard H, Madsen T, Hansen J, Chivulescu M, Christiansen MK, Carlson J, Edvardsen T, Svendsen JH, Platonov PG. 2020. Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy: Experience from the Nordic ARVC Registry. International Journal of Cardiology. 298:39-43. https://doi.org/10.1016/j.ijcard.2019.07.086

MLA

Vancouver

Author

Baturova, Maria A ; Haugaa, Kristina H ; Jensen, Henrik K ; Svensson, Anneli ; Gilljam, Thomas ; Bundgaard, Henning ; Madsen, Trine ; Hansen, Jim ; Chivulescu, Monica ; Christiansen, Morten Krogh ; Carlson, Jonas ; Edvardsen, Thor ; Svendsen, Jesper H ; Platonov, Pyotr G. / Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy : Experience from the Nordic ARVC Registry. I: International Journal of Cardiology. 2020 ; Bind 298. s. 39-43.

Bibtex

@article{431892c245da41e3ba6ce6adb2657e4c,
title = "Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy: Experience from the Nordic ARVC Registry",
abstract = "BACKGROUND: Recent studies in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have drawn attention to atrial fibrillation (AF) as an arrhythmic manifestation of ARVC and as an indicator of atrial involvement in the disease progression. We aimed to assess the prevalence of AF in the Scandinavian cohort of ARVC patients and to evaluate its association with disease clinical manifestations.METHODS: Study sample comprised of 293 definite ARVC patients by 2010 Task Force criteria (TFC2010) and 141 genotype-positive family members (total n = 434, 43% females, median age at ARVC diagnosis 41 years [interquartile range (IQR) 28-52 years]). ARVC diagnostic score was calculated as the sum of major (2 points) and minor (1 point) criteria in all categories of the TFC2010.RESULTS: AF was diagnosed in 42 patients (10%): in 41 patients with definite ARVC diagnosis (14%) vs in one genotype-positive family member (1%), p < 0.001. The median age at AF onset was 51 (IQR 38-58) years. The prevalence of AF was related to the ARVC diagnostic score: it significantly increased starting with the diagnostic score 4 (2% in those with score 3 vs 13% in those with score 4, p = 0.023) and increased further with increased diagnostic score (Somer's d value is 0.074, p < 0.001).CONCLUSION: AF is seen in 14% of definite ARVC patients and is related to the severity of disease phenotype thus suggesting AF being an arrhythmic manifestation of this cardiomyopathy indicating atrial myocardial involvement in the disease progression.",
keywords = "Arrhythmogenic cardiomyopathy, Atrial fibrillation, Diagnostic score",
author = "Baturova, {Maria A} and Haugaa, {Kristina H} and Jensen, {Henrik K} and Anneli Svensson and Thomas Gilljam and Henning Bundgaard and Trine Madsen and Jim Hansen and Monica Chivulescu and Christiansen, {Morten Krogh} and Jonas Carlson and Thor Edvardsen and Svendsen, {Jesper H} and Platonov, {Pyotr G}",
note = "Copyright {\textcopyright} 2019 Elsevier B.V. All rights reserved.",
year = "2020",
month = jan,
doi = "10.1016/j.ijcard.2019.07.086",
language = "English",
volume = "298",
pages = "39--43",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd.",

}

RIS

TY - JOUR

T1 - Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy

T2 - Experience from the Nordic ARVC Registry

AU - Baturova, Maria A

AU - Haugaa, Kristina H

AU - Jensen, Henrik K

AU - Svensson, Anneli

AU - Gilljam, Thomas

AU - Bundgaard, Henning

AU - Madsen, Trine

AU - Hansen, Jim

AU - Chivulescu, Monica

AU - Christiansen, Morten Krogh

AU - Carlson, Jonas

AU - Edvardsen, Thor

AU - Svendsen, Jesper H

AU - Platonov, Pyotr G

N1 - Copyright © 2019 Elsevier B.V. All rights reserved.

PY - 2020/1

Y1 - 2020/1

N2 - BACKGROUND: Recent studies in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have drawn attention to atrial fibrillation (AF) as an arrhythmic manifestation of ARVC and as an indicator of atrial involvement in the disease progression. We aimed to assess the prevalence of AF in the Scandinavian cohort of ARVC patients and to evaluate its association with disease clinical manifestations.METHODS: Study sample comprised of 293 definite ARVC patients by 2010 Task Force criteria (TFC2010) and 141 genotype-positive family members (total n = 434, 43% females, median age at ARVC diagnosis 41 years [interquartile range (IQR) 28-52 years]). ARVC diagnostic score was calculated as the sum of major (2 points) and minor (1 point) criteria in all categories of the TFC2010.RESULTS: AF was diagnosed in 42 patients (10%): in 41 patients with definite ARVC diagnosis (14%) vs in one genotype-positive family member (1%), p < 0.001. The median age at AF onset was 51 (IQR 38-58) years. The prevalence of AF was related to the ARVC diagnostic score: it significantly increased starting with the diagnostic score 4 (2% in those with score 3 vs 13% in those with score 4, p = 0.023) and increased further with increased diagnostic score (Somer's d value is 0.074, p < 0.001).CONCLUSION: AF is seen in 14% of definite ARVC patients and is related to the severity of disease phenotype thus suggesting AF being an arrhythmic manifestation of this cardiomyopathy indicating atrial myocardial involvement in the disease progression.

AB - BACKGROUND: Recent studies in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have drawn attention to atrial fibrillation (AF) as an arrhythmic manifestation of ARVC and as an indicator of atrial involvement in the disease progression. We aimed to assess the prevalence of AF in the Scandinavian cohort of ARVC patients and to evaluate its association with disease clinical manifestations.METHODS: Study sample comprised of 293 definite ARVC patients by 2010 Task Force criteria (TFC2010) and 141 genotype-positive family members (total n = 434, 43% females, median age at ARVC diagnosis 41 years [interquartile range (IQR) 28-52 years]). ARVC diagnostic score was calculated as the sum of major (2 points) and minor (1 point) criteria in all categories of the TFC2010.RESULTS: AF was diagnosed in 42 patients (10%): in 41 patients with definite ARVC diagnosis (14%) vs in one genotype-positive family member (1%), p < 0.001. The median age at AF onset was 51 (IQR 38-58) years. The prevalence of AF was related to the ARVC diagnostic score: it significantly increased starting with the diagnostic score 4 (2% in those with score 3 vs 13% in those with score 4, p = 0.023) and increased further with increased diagnostic score (Somer's d value is 0.074, p < 0.001).CONCLUSION: AF is seen in 14% of definite ARVC patients and is related to the severity of disease phenotype thus suggesting AF being an arrhythmic manifestation of this cardiomyopathy indicating atrial myocardial involvement in the disease progression.

KW - Arrhythmogenic cardiomyopathy

KW - Atrial fibrillation

KW - Diagnostic score

U2 - 10.1016/j.ijcard.2019.07.086

DO - 10.1016/j.ijcard.2019.07.086

M3 - Journal article

C2 - 31387820

VL - 298

SP - 39

EP - 43

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

ER -