Association mapping and disease: Evolutionary perspectives

Søren Besenbacher*, Thomas Mailund, Bjarni J. Vilhjálmsson, Mikkel H. Schierup

*Corresponding author af dette arbejde

Publikation: Bidrag til bog/antologi/rapport/proceedingBidrag til bog/antologiForskningpeer review

Abstract

In this chapter, we give a short introduction to the genetics of complex diseases emphasizing evolutionary models for disease genes and the effect of different models on the genetic architecture, and we give a survey of the state-of-the-art of genome-wide association studies (GWASs).

OriginalsprogEngelsk
TitelEvolutionary genomics : Statistical and computational methods
RedaktørerMaria Anisimova
Antal sider21
ForlagSpringer
Publikationsdato2019
Udgave2
Sider533-553
Kapitel17
ISBN (Trykt) 978-1-4939-9073-3
ISBN (Elektronisk)978-1-4939-9074-0
DOI
StatusUdgivet - 2019
NavnMethods in Molecular Biology
Vol/bind1910
ISSN1064-3745

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