Appreciable uncertainty regarding benefits and risks in the treatment of bacterial vaginosis to prevent preterm birth

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisKommentar/debatForskningpeer review


  • Thor Haahr
  • Anne S Ersbøll, Department of Obstetrics, Copenhagen University Hospital Rigshospitalet, Copenhagen.
  • ,
  • Mona A Karlsen, Department of Obstetrics, Copenhagen University Hospital Rigshospitalet, Copenhagen.
  • ,
  • Jens Svare, Department of Obstetrics and Gynecology, Copenhagen University Hospital Herlev Gentofte, Herlev.
  • ,
  • Kirstine Sneider
  • Lene Hee, Department of Obstetrics and Gynecology, Nordsjaellands Hospital, Hillerød.
  • ,
  • Louise K Weile, Department of Gynecology and Obstetrics, Odense University Hospital, Odense.
  • ,
  • Agnes Ziobrowska-Bech
  • ,
  • Claus Østergaard, Department of Clinical Microbiology, Vejle Hospital, Vejle.
  • ,
  • Jørgen S Jensen, Statens Serum Institute, Copenhagen
  • ,
  • Rikke B Helmig
  • Niels Uldbjerg

As part of his speeches, the Roman senator Cato the Elder frequently uttered "Carthago delenda est" (Carthage must be destroyed). Similarly, Lamont and colleagues frequently utter that the "wrong patients with the wrong diagnosis were given wrong antibiotics at the wrong gestational age". We respect that Lamont and colleagues find it difficult to accept meta-analyses, which "cut a toe and a bit of a heel" to merge evidence from more publications, and we certainly cannot exclude the possibility that future research will change clinical practice. However, in contrast to Lamont and colleagues, we emphasize that not only statistical significance but also other aspects should be taken into consideration in the development of clinical recommendations (1). This article is protected by copyright. All rights reserved.

TidsskriftActa Obstetricia et Gynecologica Scandinavica
Sider (fra-til)251–252
Antal sider2
StatusUdgivet - feb. 2017

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